EC Number |
Metals/Ions |
Reference |
---|
3.1.4.12 | Ca2+ |
- |
135188, 678083 |
3.1.4.12 | Ca2+ |
activated by micromolar concentrations of Ca2+ (0.0001 or 0.00001 mM) under Mg2+-free conditions, ceramide generation is dependent upon the calcium ionophore A23187, nSMase is not activated by Ca2+ cations in the presence of 1 mM Mg2+ |
705258 |
3.1.4.12 | Ca2+ |
activation of hemolysis at 2 mM, strong inhibition at 10 mM |
651708 |
3.1.4.12 | Ca2+ |
Km: 0.0191 mM, activation of sphingomyelinase activity in the order of decreasing efficiency Co2+, Mn2+, Mg2+, Ca2+, Sr2+ |
665716 |
3.1.4.12 | Ca2+ |
lysosomal enzyme, stimulation at pH 5-7.5 |
135163 |
3.1.4.12 | Ca2+ |
partly restores the EDTA-inhibited enzyme activity |
135166 |
3.1.4.12 | Ca2+ |
plays a role in enzyme regulation by non-substrate lipids |
679082 |
3.1.4.12 | Ca2+ |
slight activation when water-soluble substrates are used |
135157 |
3.1.4.12 | Ca2+ |
slightly activates, Km is 1.40 mM |
730073 |
3.1.4.12 | Cd2+ |
- |
135148 |