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EC Number	Metals/Ions	Commentary	Reference
2.7.9.2	Ca2+	enzyme contains 1 Ca atom per subunit	645478
2.7.9.2	Co2+	requires divalent cations in the forward reaction, 93% of the activity with Mg2+	645478
2.7.9.2	Iron	0.1-0.4 g-atoms per subunit, no functional part of the enzyme	645478
2.7.9.2	K+	50% increased activity at 100 mM	645478
2.7.9.2	Mg2+	10 mM, required	676065
2.7.9.2	Mg2+	divalent metal ion Mg2+ or Mn2+ required for forward reaction	645468, 645472
2.7.9.2	Mg2+	inhibition at high concentrations of Mg2+ or Mn2+	645468
2.7.9.2	Mg2+	Mg2+ is more effective	645472
2.7.9.2	Mg2+	required	737626, 737850, 744178
2.7.9.2	Mg2+	requires divalent cations in the forward reaction, Mg2+ is most effective	645478

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Release 2023.1 (January 2023)