EC Number   |
Metals/Ions |
Reference |
|---|
    2.7.1.30 | (NH4)2SO4 |
activates |
641289 |
| 2.7.1.30 | Co2+ |
best effect, may be replaced by Zn2+ |
641319 |
| 2.7.1.30 | KCl |
0.04 M, stimulates 30% at neutral pH |
641294 |
| 2.7.1.30 | KCl |
stimulates |
641307 |
| 2.7.1.30 | Mg2+ |
essentially required for activity, maximum activity at the optimum Mg2+ to ATP molar ratio of [0.12-0.3]. Subsequent increase of Mg2+ to ATP molar ratio higher than the values in the optimum region suppresses the enzyme activity to a non-zero asymptotic value. The enzyme exhibits two-step kinetics as a function of ATP at a fixed Mg2+ concentration due to the formation of multiple Mg-ATP complexes at different Mg2+ to ATP molar ratio. The interaction of Mg2+ and ATP generates Mg-ATP complexes of various physical and chemical features in which the product composition depends on Mg2+ to ATP molar ratio among other factors such as pH, temperature, availability of other polyvalent chelating anions as well as cations and their concentration |
761883 |
| 2.7.1.30 | Mg2+ |
maximum with 2.5 mM Mg2+ |
641290 |
| 2.7.1.30 | Mg2+ |
Mg2+-ATP-dependent |
722712 |
| 2.7.1.30 | Mg2+ |
ommision of Mg2+ abolishes activity |
641296 |
| 2.7.1.30 | Mg2+ |
other metal ions cannot substitute for Mg2+ |
641290, 641296 |
| 2.7.1.30 | Mg2+ |
required |
641287, 641290, 641291, 641295, 641300, 641323, 722839, 738722, 760456, 760620, 760718, 761002, 761058, 761154, 761192, 761561, 761627, 761751, 761816 |
