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EC Number	Metals/Ions	Commentary	Reference
2.4.2.30	Ba2+	enhances activity	637991
2.4.2.30	Fe2+	enzyme binds iron through a Fe-S center, which is crucial for the catalytic activity	722703
2.4.2.30	Mg2+	-	675627, 694800, 695219
2.4.2.30	Mg2+	0.1 mM, 4.1fold activation	725034
2.4.2.30	Mg2+	activates	637997
2.4.2.30	Mg2+	divalent cation required, Mg2+ preferred to Mn2+, optimal concentration 5 mM	637995
2.4.2.30	Mg2+	enhances both the automodification and poly(ADP-ribosyl)ation of histone H1	637991
2.4.2.30	Mg2+	required	672048
2.4.2.30	Mn2+	divalent cation required, Mg2+ preferred to Mn2+	637995
2.4.2.30	Mn2+	required for activity, cannot be substituted by Mg2+	671826

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Release 2023.1 (January 2023)