EC Number |
Metals/Ions |
Reference |
---|
1.6.1.1 | Ca2+ |
- |
392582, 392583, 392584, 392595 |
1.6.1.1 | Ca2+ |
10-20fold activation of NAD+ reduction by NADPH at alkaline pH in cell-free extracts |
392577 |
1.6.1.1 | Ca2+ |
Ca2+-dependent allosteric conformational change, competitive inhibition of activation by Mg2+ |
392579 |
1.6.1.1 | EDTA |
slight activating at low buffer concentrations |
392586 |
1.6.1.1 | K+ |
no full activation compared to Ca2+ |
392584 |
1.6.1.1 | Mg2+ |
10-20fold activation of NAD+ reduction by NADPH at alkaline pH in cell-free extracts |
392577 |
1.6.1.1 | Mg2+ |
no full activation even at saturation concentrations |
392584 |
1.6.1.1 | Mn2+ |
compared to Ca2+ 10 times higher concetrations are required to obtain the same degree of activation |
392584 |
1.6.1.1 | more |
not influenced by Na+, Rb+, K+, Li+, and Mg2+ |
725040 |