EC Number   |
Metals/Ions |
Reference |
|---|
    1.5.1.3 | CaCl2 |
- |
392283 |
| 1.5.1.3 | Cs+ |
activation of mutant type enzyme at 0.2 mM, decrease of wild type enzyme activity above 0.1 mM |
392235 |
| 1.5.1.3 | K+ |
activation of mutant type enzyme activity at 0.2 mM, decrease of wild type enzyme activity above 0.1 mM |
392235 |
| 1.5.1.3 | K+ |
stimulation |
392247, 392258, 392260, 392264, 392272, 392273 |
| 1.5.1.3 | KCl |
dihydrofolate reductase hvDHFR1 and hvDHFR2 unfold at KCl concentrations below 0.5 M. Above 1 M, the KCl dependence of the dihydrofolate reductase activities can be attributed to the effect of salt on substrate affinity |
728128 |
| 1.5.1.3 | KCl |
maximal activity at 0.5 M |
655633 |
| 1.5.1.3 | KCl |
steady increase in activity from 0 to 1 M KCl |
655633 |
| 1.5.1.3 | KCl |
the optimal ionic strength for both enzymes requires 100 mM KCl, with DHFR displaying 2.5fold activation and TS 4.5fold activation |
743569 |
| 1.5.1.3 | Li+ |
activation of mutant type enzyme at 0.2 mM, decrease of wild type enzyme activity above 0.1 mM |
392235 |
| 1.5.1.3 | Na+ |
activates |
392242 |
