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EC Number Metals/Ions Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.21.99.3Se selenoenzyme 659569
Display the word mapDisplay the reaction diagram Show all sequences 1.21.99.3Se2+ the enzyme is a selenoenzyme encoded by the DIO3 gene. The DIO3 genomic structure contains a single exon and, at the 3'-UTR, a specific RNA structure, named SECIS (selenocysteine insertion element), that is crucial for the insertion of the selenocysteine residue and for maximal enzymatic catalytic efficiency. The DIO3 gene is imprinted, with preferential expression of the paternal allele. It belongs to a cluster of imprinted regions, at the DLK1-DIO3 locus 733907
Display the word mapDisplay the reaction diagram Show all sequences 1.21.99.3selenium selenoprotein 716049
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