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EC Number Metals/Ions Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.49Ca2+ Ca2+-levels affect separase function, C-terminal region contains a Ca2+-binding motif 638862
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.49Ca2+ the enzyme contains a Ca2+-binding EF-hand motif, which can possibly affect separase interaction with the spindle, similar to the budding yeast Esp1, or alternatively Ca2+ might be a critical component for (auto-)catalysis 718194
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