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Results 1 - 10 of 12 > >>
EC Number
Metals/Ions
Commentary
Reference
Ca2+
optimal at concentration of 50 mM, inhibition above 200 mM
Iron
regulation of erythroid-specific isoform ALAS-2 via 5'-iron responsive element, i.e. IRE
Li+
in Mg2+-containing medium: at 100 mM no effect on activity, higher concentrations are totally inhibitory
Li+
in Mg2+-containing medium: at 100 mM no effect on activity, higher concentrations are totally inhibitory; optimal at 0.5 M, not inhibitory up to 1 M
Mg2+
activates
Mg2+
inhibition of complex form, stimulation of stripped form
Mg2+
optimal at concentration of 50 mM, inhibition above 200 mM
more
partially purified enzyme requires high cation concentrations, equivalent to 0.3 M NaCl, for maximum activation, monovalent cations, i.e. Na+, K+, Li+, Rb+ or NH4+, in concentrations from 0.15 M to 0.30 M or divalent cations, i.e. Mg2+, Ca2+ or Mn2+, at lower concentrations of 0.03 M to 0.10 M are effective
Na+
in Mg2+-containing medium: at 100 mM no effect on activity, higher concentrations are totally inhibitory
Na+
in Mg2+-containing medium: at 100 mM no effect on activity, higher concentrations are totally inhibitory; optimal at 0.5 M, not inhibitory up to 1 M
Results 1 - 10 of 12 > >>