EC Number |
Metals/Ions |
Reference |
---|
4.2.1.3 | Iron |
the enzyme contains a [4Fe-4S]2+ cluster |
650198 |
4.2.1.3 | Iron |
the enzyme hosts an interconvertible [3Fe-4S] cluster |
651095 |
4.2.1.3 | Iron |
under iron-replete conditions, enzyme binds a [4Fe-4S] cluster und functions as cytosolic aconitase. Under iron shortage, enzyme is involved in translational control as an iron regulatory protein |
682876 |
4.2.1.3 | Iron |
[4Fe-4S] cluster |
679969 |
4.2.1.3 | Iron |
[4Fe-4S] cluster. The [4Fe-4S] cluster loaded form of the IscU [Fe-S] cluser scaffolding protein can be used for intact cluster transfer to an apo form of aconitase A. IscU mutant D39A is an effective inhibitor of IscU-directed activation of apo-aconitase A |
678291 |
4.2.1.3 | Mg2+ |
- |
696416, 697220 |
4.2.1.3 | more |
IRP1 is a cytosolic isozyme devoid of labile Fe2+ |
696168 |
4.2.1.3 | Zn |
an X-ray fluorescence measurement performed on a gold-derivative crystal shows the unexpected presence of zinc, in addition to gold and iron |
663546 |
4.2.1.3 | [4Fe-4S] center |
acon harbors a single unligated iron atom in its [4Fe-4S], enzyme is in this respect unique in mitochondria |
730672 |