EC Number   |
Metals/Ions |
Reference |
|---|
   3.4.22.53 | Ca2+ |
requires millimolar calcium concentrations for activation |
709641 |
| 3.4.22.53 | Ca2+ |
requires millimolar order calcium ions for activation |
644032 |
| 3.4.22.53 | Ca2+ |
the Ca2+ dependency of mitochondrial m-calpain is similar to that of cytosolic m-calpain, 1 mM Ca2+ activates. |
707559 |
| 3.4.22.53 | Ca2+ |
treatment of the endoplasmic reticulum with Ca2+ (5 mM) dissociates m-calpain-calpastatin association leading to the activation of m-calpain |
708954 |
| 3.4.22.53 | Ca2+ |
wild-type enzyme has a Kd-value of 0.325 mM |
644047 |
| 3.4.22.53 | Co2+ |
5 mM, activates |
644031 |
| 3.4.22.53 | Cu2+ |
activates |
644052 |
| 3.4.22.53 | K+ |
5 mM, activates in presence of 5 mM Ca2+ |
644031 |
| 3.4.22.53 | Mg2+ |
1 mM decreases the Ca2+-requirement for maximal activity from 0.4 mM to 0.3 mM. Synergistic activating effect with Ca2+ |
644027 |
| 3.4.22.53 | Mg2+ |
5 mM, activates in presence of 5 mM Ca2+ |
644031 |
