EC Number |
Localization |
GeneOntology No. |
Reference |
---|
5.6.1.2 | axon |
motor axon |
GO:0030424 AmiGO QuickGO |
670210 |
5.6.1.2 | axon |
Tctex-1 is enriched in growing axons of cultured hippocampal neurons. The cytoplasmic dynein light chain Tctex-1 plays a key role in multiple steps of hippocampal neuron development, including initial neurite sprouting, axon specification, and later dendritic elaboration. The neuritogenic effects elicited by Tctex-1 are independent from its cargo adaptor role for dynein motor transport. The selective high level of Tctex-1 at the growth cone of growing axons drives fast neurite extension by modulating actin dynamics and also Rac1 activity |
GO:0030424 AmiGO QuickGO |
668370 |
5.6.1.2 | cilium |
- |
GO:0005929 AmiGO QuickGO |
247011, 247019, 247025, 247029, 247030, 247032, 670690 |
5.6.1.2 | cilium |
axoneme |
GO:0005929 AmiGO QuickGO |
-, 720341 |
5.6.1.2 | cytoplasm |
- |
GO:0005737 AmiGO QuickGO |
-, 210563, 210568, 247007, 247021, 247022, 654443, 655190, 667580, 668182, 668370, 669383, 669949, 669959, 670186, 670199, 687577, 688691, 689741, 712890, 712983, 720547, 735286, 751171, 751690, 752035 |
5.6.1.2 | cytoplasm |
cytoplasmic dynein is the sole motor for microtubule-based ER motility throughout the early stages of development |
GO:0005737 AmiGO QuickGO |
210551 |
5.6.1.2 | cytoplasm |
microtubule-associated enzyme |
GO:0005737 AmiGO QuickGO |
247006 |
5.6.1.2 | cytoplasm |
the presence of cytoplasmic dynein is also important for the microtubule plus-end accumulation of NADF |
GO:0005737 AmiGO QuickGO |
656759 |
5.6.1.2 | dendrite |
dendritic spines |
GO:0030425 AmiGO QuickGO |
669959 |
5.6.1.2 | endoplasmic reticulum |
redistribution of endoplasmic reticulum during oocyte maturation is dynein-driven and cell cycle-dependent |
GO:0005783 AmiGO QuickGO |
686282 |