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Results 1 - 10 of 19 > >>
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EC Number Localization Commentary GeneOntology No. Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.81cell associated - - 639004, 644071
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.81cell surface - GO:0009986 AmiGO QuickGO 667528, 668181, 668305, 668372, 668407
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.81cytoplasm in untreated cells GO:0005737 AmiGO QuickGO 699697
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.81endoplasmic reticulum - GO:0005783 AmiGO QuickGO 753694
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.81endoplasmic reticulum identification of an endoplasmic reticulum retention motif within the ADAM10 intracellular C-terminal tail. Sequential deletion/mutagenesis analyses shows that an arginine-rich (723RRR) sequence is responsible for the retention of ADAM10 in the endoplasmic reticulum and its inefficient surface trafficking. Mutating the second arginine to alanine is sufficient to allow endoplasmic reticulum exit and surface expression in both heterologous cells and hippocampal neurons GO:0005783 AmiGO QuickGO 709083
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.81endosome - GO:0005768 AmiGO QuickGO 696395
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.81Golgi apparatus - GO:0005794 AmiGO QuickGO 753694, 754458
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.81Golgi apparatus most of the activity of the enzyme GO:0005794 AmiGO QuickGO 644074
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.81membrane - GO:0016020 AmiGO QuickGO 668181, 668275, 669926
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.81membrane the typical multidomain structure of ADAM10 as a type I integral transmembrane protein consists of a prodomain, a catalytical domain with a conserved zinc binding sequence, a cysteine-rich disintegrin-like domain, a transmembrane domain and a rather short cytoplasmic domain GO:0016020 AmiGO QuickGO 708492
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