EC Number |
Localization |
GeneOntology No. |
Reference |
---|
3.4.24.79 | cell surface |
- |
GO:0009986 AmiGO QuickGO |
735323 |
3.4.24.79 | cell surface |
detachment of pregnancy-associated plasma protein-A requires the formation of intermolecular proteinase-inhibitor disulfide bonds and glycosaminoglycan covalently bound to the inhibitor, mechanism, overview, the PAPP-A-proMBP complex is unable to bind to the cell surface |
GO:0009986 AmiGO QuickGO |
683645 |
3.4.24.79 | cell surface |
surface association of PAPP-A accounts for its colocalization with activated macrophages in human atherosclerotic plaque, immunohistochemic analysis, overview |
GO:0009986 AmiGO QuickGO |
683050 |
3.4.24.79 | extracellular |
- |
- |
683365, 683504, 683645, 683969 |
3.4.24.79 | more |
the PAPP-A-proMBP complex is formed at the cell surface in vivo rather than in the circulation, the redox potential of the tissue microenvironment controls the process, chondroitin or dermatan sulfate do not have any effect on complex formation |
- |
683645 |
3.4.24.79 | soluble |
- |
- |
638943 |
3.4.24.79 | soluble |
PAPP-A reversibly binds to cell surface, while PAPP-A2 does not |
- |
638939 |
3.4.24.79 | soluble |
secreted |
- |
638932, 638933, 638934, 638935, 638945 |