EC Number   |
Localization |
GeneOntology No. |
Reference |
|---|
   3.4.22.60 | cytoplasm |
- |
GO:0005737 AmiGO QuickGO |
670408, 699310, 717785, 731608, 731701 |
| 3.4.22.60 | cytosol |
- |
GO:0005829 AmiGO QuickGO |
647663, 647664, 669391, 669946 |
| 3.4.22.60 | more |
active caspase-7 colocalizes with internalized TNF-R1 receptosomes, molecular components of a potential signalling cascade from TNF-R1 to A-SMase via caspase-7 actually localize in the same subcellular compartment. Direct association of caspase-7 and A-SMase within TNF receptosomes |
- |
717539 |
| 3.4.22.60 | more |
human caspase-7 is not a nuclear caspase removal of the N-peptide does not allow an active transport or accumulation of human caspase-7 in the nuclei |
- |
647669 |
| 3.4.22.60 | more |
no translocation of active caspase-7 to the nucleus |
- |
699310 |
| 3.4.22.60 | nucleus |
- |
GO:0005634 AmiGO QuickGO |
669391, 670408 |
| 3.4.22.60 | nucleus |
caspase-7 is activated and accumulates in the nucleus. A prodomain of caspase-7, 31 amino acid residues, inhibits both the apoptosis-inducing activity and the nuclear localization, removal of the prodomain induces both the nuclear import of the catalytic protease and the cell killing activity |
GO:0005634 AmiGO QuickGO |
647667 |
| 3.4.22.60 | plasma membrane |
juxtamembrane structures |
GO:0005886 AmiGO QuickGO |
647663 |
| 3.4.22.60 | spheroplast |
spheroids of HT-29 cells |
- |
699310 |
