EC Number   |
Localization |
GeneOntology No. |
Reference |
|---|
   3.1.26.12 | chloroplast |
soluble fraction |
GO:0009507 AmiGO QuickGO |
690026 |
| 3.1.26.12 | cytoplasmic membrane |
- |
- |
-, 751598 |
| 3.1.26.12 | cytoplasmic membrane |
enzyme membrane binding induces changes in secondary protein structure and enzymatic activation by stabilizing the protein-folding state and increasing its binding affinity for ist substrate |
- |
730815 |
| 3.1.26.12 | cytoplasmic membrane |
the association of RNase E with the cytoplasmic membrane is required for optimal cell growth in Escherichia coli |
- |
-, 751494 |
| 3.1.26.12 | cytoskeleton |
RNase E and the other constituents of the RNA degradosome are components of the bacterial cytoskeleton, degradosome components, i.e. RNase E, helicase B, polynucleotide hosphorylase, and enolase, are organized as helical filamentous structures that coil around the length of the cell. Formation of the RNaseE cytoskeletal-like structure requires an internal domain of the protein that does not include the domains required for any of its known interactions or the minimal domain required for endonuclease activity, but is independent of MreB and MinD cytoskeletal structures, mechanism of assembly, overview |
GO:0005856 AmiGO QuickGO |
689760 |
| 3.1.26.12 | intracellular |
- |
GO:0005622 AmiGO QuickGO |
-, 750962 |
| 3.1.26.12 | intracellular |
RNaseE is organized as a cytoskeletal structure in vivo. RNaseE and the other known degradosome components (RNA helicase B, polynucleotide phosphorylase, and enolase) are organized as helical filamentous structures that coil around the length of the cell. These resemble the helical structures formed by the MreB and MinD cytoskeletal proteins. Formation of the RNaseE cytoskeletal-like structure requires an internal domain of the protein that does not include the domains required for any of its known interactions or the minimal domain required for endonuclease activity. The constituents of the RNA degradosome are components of the Escherichia coli cytoskeleton, either assembled as a primary cytoskeletal structure or secondarily associated with another underlying cytoskeletal element |
GO:0005622 AmiGO QuickGO |
-, 752028 |
| 3.1.26.12 | membrane |
- |
GO:0016020 AmiGO QuickGO |
670298 |
| 3.1.26.12 | membrane |
localized to the inner cytoplasmic membrane, segment-A is necessary and sufficient for RNase E binding to membranes |
GO:0016020 AmiGO QuickGO |
-, 694243 |
| 3.1.26.12 | more |
no enzyme in the mitochondria |
- |
690026 |
