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EC Number
Localization
Commentary
GeneOntology No.
Reference
2.7.7.18
cytoplasm
-
GO:0005737
AmiGO
QuickGO
703814
,
739510
2.7.7.18
Golgi apparatus
isoform NMNAT2 localizes to the cis-Golgi and endoplasmic reticulum-Golgi intermediate compartment. It is palmitoylated at two adjacent cysteine residues of its isoform-specific domain and thereby anchored at the cytoplasmic surface
GO:0005794
AmiGO
QuickGO
722676
2.7.7.18
mitochondrion
-
GO:0005739
AmiGO
QuickGO
703814
2.7.7.18
mitochondrion
isoform NMNAT3 is targeted to mitochondria by its N-terminus
GO:0005739
AmiGO
QuickGO
722676
2.7.7.18
more
the three human isoforms NMNAT1-3 are localized to the nucleus, the Golgi complex, and mitochondria. Their genes contain unique exons that encode isoform-specific domains to mediate subcellular targeting and post-translational modifications. These domains are dispensable for catalytic activity
-
722676
2.7.7.18
nucleus
-
GO:0005634
AmiGO
QuickGO
703814
2.7.7.18
nucleus
sequence of isoform NMNAT1 contains a predicted nuclear localization signal
GO:0005634
AmiGO
QuickGO
722676
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