EC Number   |
Localization |
GeneOntology No. |
Reference |
|---|
   2.3.1.22 | endoplasmic reticulum |
- |
GO:0005783 AmiGO QuickGO |
659195, 659335, 701625 |
| 2.3.1.22 | endoplasmic reticulum |
integral membrane protein, the C-terminus is exposed to the cytosol, while the N-terminus is partially buried in the ER membrane. Domains that are important for catalysis face the cytosol. Both transmembrane domains of MGAT2 are important for its ER localization, and MGAT2 is present in mitochondrial-associated membranes |
GO:0005783 AmiGO QuickGO |
756081 |
| 2.3.1.22 | endoplasmic reticulum |
MGAT1 localizes to the endoplasmic reticulum under normal conditions, and colocalizes to lipid droplets under conditions of enriching fatty acids, contributing to TAG synthesis and LD expansion |
GO:0005783 AmiGO QuickGO |
756283 |
| 2.3.1.22 | endoplasmic reticulum membrane |
- |
GO:0005789 AmiGO QuickGO |
736458 |
| 2.3.1.22 | lipid droplet |
MGAT1 localizes to the endoplasmic reticulum under normal conditions, and colocalizes to lipid droplets under conditions of enriching fatty acids, contributing to TAG synthesis and LD expansion |
GO:0005811 AmiGO QuickGO |
756283 |
| 2.3.1.22 | lipid particle |
mainly |
- |
-, 659060 |
| 2.3.1.22 | membrane |
- |
GO:0016020 AmiGO QuickGO |
659670, 672340, 675260 |
| 2.3.1.22 | membrane |
for the enzyme activity, both the N-terminal transmembrane domain and catalytic HPHG motif are required. The transmembrane domain consists of two hydrophobic regions in the N-terminus, the consensus sequence FLXLXXXn, a putative neutral lipid-binding domain, exists in the first transmembrane domain |
GO:0016020 AmiGO QuickGO |
756283 |
| 2.3.1.22 | membrane |
small enzyme amout |
GO:0016020 AmiGO QuickGO |
-, 659060 |
| 2.3.1.22 | membrane |
transmembrane protein |
GO:0016020 AmiGO QuickGO |
659195 |
