EC Number   |
Localization |
GeneOntology No. |
Reference |
|---|
   2.1.1.320 | cytoplasm |
- |
GO:0005737 AmiGO QuickGO |
-, 734308, 735156, 757904 |
| 2.1.1.320 | cytoplasm |
high levels of cytoplasmic PRMT5 are detected in 20.5% of non-small cell lung carcinomas and in 16.5% of pulmonary neuroendocrine tumors |
GO:0005737 AmiGO QuickGO |
733704 |
| 2.1.1.320 | cytoplasm |
isoform PRMT5 and p44/MED50/WD45/WDR77 colocalize in the cytoplasm, and both are required for the growth of prostate cancer cells in an PRMT5 methyltransferase activity-dependent manner |
GO:0005737 AmiGO QuickGO |
735066 |
| 2.1.1.320 | cytoplasm |
predominant localization |
GO:0005737 AmiGO QuickGO |
659149 |
| 2.1.1.320 | cytosol |
- |
GO:0005829 AmiGO QuickGO |
733280, 756193 |
| 2.1.1.320 | cytosol |
PRMT5 enzyme localization is concentrated in the cytosolic, membrane, and myonuclear compartments of mature myofibers |
GO:0005829 AmiGO QuickGO |
755764 |
| 2.1.1.320 | Golgi apparatus |
isoform PRMT5 localizes to the Golgi apparatus and forms complexes with several components involved in Golgi apparatus ribbon formation and vesicle tethering. PRMT5 interacts with the golgin GM130 |
GO:0005794 AmiGO QuickGO |
733633 |
| 2.1.1.320 | Golgi apparatus |
original isoform PRMT5L mainly colocalizes with Giantin, a Golgi marker |
GO:0005794 AmiGO QuickGO |
733417 |
| 2.1.1.320 | membrane |
PRMT5 enzyme localization is concentrated in the cytosolic, membrane, and myonuclear compartments of mature myofibers |
GO:0016020 AmiGO QuickGO |
755764 |
| 2.1.1.320 | microtubule |
coexpression of candidate tumor suppressor gene RASSF1A and PRMT5 leads to a redistribution of PRMT5 from the cytosol to stabilized microtubules |
GO:0005874 AmiGO QuickGO |
733280 |
