EC Number   |
Localization |
GeneOntology No. |
Reference |
|---|
    1.14.13.9 | cytoplasmic vesicle |
- |
GO:0031410 AmiGO QuickGO |
348532 |
| 1.14.13.9 | membrane |
- |
GO:0016020 AmiGO QuickGO |
764298 |
| 1.14.13.9 | membrane |
enzyme is hydrophobis and contains 2 transmembrane segments |
GO:0016020 AmiGO QuickGO |
-, 658919 |
| 1.14.13.9 | membrane |
specifically, KMO is localised to the outer membrane of mitochondria where it associates with the lipid membrane using C-terminal transmembrane domains, which are also crucial for the catalytic activity of KMO |
GO:0016020 AmiGO QuickGO |
764034 |
| 1.14.13.9 | microsome |
- |
- |
-, 764034, 764296, 764298 |
| 1.14.13.9 | mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
-, 763915, 764296 |
| 1.14.13.9 | mitochondrial membrane |
the C terminus of the enzyme contains a putative outer mitochondrial membrane-targeting sequence and this portion of the molecule is required enzyme function |
GO:0031966 AmiGO QuickGO |
742349 |
| 1.14.13.9 | mitochondrial outer membrane |
- |
GO:0005741 AmiGO QuickGO |
-, 348514, 348517, 348518, 348524, 348528, 348531, 764641, 764695, 764728, 765242, 765436, 765487 |
| 1.14.13.9 | mitochondrial outer membrane |
KMO has two transmembrane domains, KMO is actually a single-pass transmembrane protein, with the other transmembrane domain lying laterally along the membrane, where it forms part of the ligand-binding pocket. Membrane-bound structure, overview |
GO:0005741 AmiGO QuickGO |
764520 |
| 1.14.13.9 | mitochondrial outer membrane |
KMO is localized to the outer mitochondrial membrane in eukaryotic organisms |
GO:0005741 AmiGO QuickGO |
-, 765643 |
