EC Number |
Recommended Name |
Localization |
GeneOntology No. |
Reference |
---|
2.3.2.24 | (E3-independent) E2 ubiquitin-conjugating enzyme |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
759177, 759488 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
nucleus |
membrane |
GO:0005634 AmiGO QuickGO |
486627 |
2.3.1.67 | 1-alkylglycerophosphocholine O-acetyltransferase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
487384 |
2.3.1.67 | 1-alkylglycerophosphocholine O-acetyltransferase |
nucleus |
neuronal nuclear fraction |
GO:0005634 AmiGO QuickGO |
487393 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
641805, 662073, 674573, 675000, 739269 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
nucleus |
enzyme form PI4K92 |
GO:0005634 AmiGO QuickGO |
641806 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
nucleus |
PI4KIIIbeta shuttles through the nucleus |
GO:0005634 AmiGO QuickGO |
723791 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
nucleus |
Pik1 shuttles through the nucleus. Nuclear accumulation of Pik1 is promoted by nutrient, e.g. glucose, deprivation, a condition that also results in the release of PI4K effectors from Golgi membranes and slowing of the rate of secretion |
GO:0005634 AmiGO QuickGO |
723791 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
nucleus |
PtdIns 4-kinase Pik1 |
GO:0005634 AmiGO QuickGO |
-, 722789 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
nucleus |
the chilli leaf curl virus Rep protein directly interacts with PI4KII protein and influences nuclear occurrence of the enzyme |
GO:0005634 AmiGO QuickGO |
759796 |
2.7.1.68 | 1-phosphatidylinositol-4-phosphate 5-kinase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
676432, 738288, 738659, 759964 |
2.7.1.68 | 1-phosphatidylinositol-4-phosphate 5-kinase |
nucleus |
isozyme PIP5Kalpha |
GO:0005634 AmiGO QuickGO |
722784 |
2.7.1.149 | 1-phosphatidylinositol-5-phosphate 4-kinase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
686033, 737638, 759023 |
2.7.1.149 | 1-phosphatidylinositol-5-phosphate 4-kinase |
nucleus |
isoform PI5P4Kalpha is chromatin-associated. In the exponential phase of growth PI5P4Kbeta is primarily cytoplasmic but translocates to the nucleus upon growth into the stationary phase or upon serum starvation |
GO:0005634 AmiGO QuickGO |
758748 |
2.7.1.149 | 1-phosphatidylinositol-5-phosphate 4-kinase |
nucleus |
isoform PI5P4Kbeta |
GO:0005634 AmiGO QuickGO |
737638 |
2.7.1.149 | 1-phosphatidylinositol-5-phosphate 4-kinase |
nucleus |
isozyme PIP4Kbeta can modulate the nuclear localization of isozyme PIP4Kalpha |
GO:0005634 AmiGO QuickGO |
721525 |
2.7.1.149 | 1-phosphatidylinositol-5-phosphate 4-kinase |
nucleus |
PI5P4Kalpha is membrane-bound in DT40 cells with a significant amount of endogenous PI5P4Kalpha in the nucleus |
GO:0005634 AmiGO QuickGO |
721247 |
2.7.1.149 | 1-phosphatidylinositol-5-phosphate 4-kinase |
nucleus |
PIPKIIbeta |
GO:0005634 AmiGO QuickGO |
721493 |
1.14.14.32 | 17alpha-hydroxyprogesterone deacetylase |
nucleus |
perinucleus |
GO:0005634 AmiGO QuickGO |
738346 |
2.1.1.183 | 18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
705680 |
2.1.1.309 | 18S rRNA (guanine1575-N7)-methyltransferase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
736779, 737229 |
2.7.7.84 | 2'-5' oligoadenylate synthase |
nucleus |
association of this form of OAS with membranes of the nuclear envelope and the rough endoplasmic reticulum |
GO:0005634 AmiGO QuickGO |
721753 |
2.4.99.20 | 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase |
nucleus |
0.4 nM/min*mg |
GO:0005634 AmiGO QuickGO |
724210 |
2.7.1.160 | 2'-phosphotransferase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
685412 |
1.3.1.74 | 2-alkenal reductase [NAD(P)+] |
nucleus |
At-AER protein fused with the Aequorea victoria green fluorescent protein localizes in cytosol and the nucleus in Bright-Yellow 2 cells of tabacco |
GO:0005634 AmiGO QuickGO |
676581 |
2.1.1.287 | 25S rRNA (adenine645-N1)-methyltransferase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
-, 758419 |
2.1.1.310 | 25S rRNA (cytosine2870-C5)-methyltransferase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
-, 737084 |
2.1.1.B128 | 28S rRNA (adenine1322-N1)-methyltransferase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
758419 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
nucleus |
PDE4 (56%) and PDE3 (44%) are the main cyclic phosphodiesterase activities in cardiac nuclei |
GO:0005634 AmiGO QuickGO |
135264 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
nucleus |
splice variant PDE9A1 |
GO:0005634 AmiGO QuickGO |
651412 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
nucleus |
enzyme isoform PDE1A is predominantly cytoplasmic in medial contractile vascular smoth muscle cell and nuclear in neointimal synthetic vascular smoth muscle cell. Nuclear enzyme isoform PDE1A is important in vascular smoth muscle cell growth and survival |
GO:0005634 AmiGO QuickGO |
679248 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
nucleus |
PDE4 (56%) and PDE3 (44%) are the main cyclic phosphodiesterase activities in cardiac nuclei |
GO:0005634 AmiGO QuickGO |
135264 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
nucleus |
PDE9A localizes to the nucleus in the brain |
GO:0005634 AmiGO QuickGO |
751697 |
2.7.7.92 | 3-deoxy-D-glycero-D-galacto-nonulopyranosonate cytidylyltransferase |
nucleus |
the crucial nuclear localization signal in the fish enzyme is bipartite and the functionality depends on a free N-terminus. Nuclear transport and enzymatic activity are independent functions. The sequence K5K6R7 is sufficient to direct GFP to the nucleus, and is necessary for the nuclear import of the CMP-Sia-synthetase in fish cells |
GO:0005634 AmiGO QuickGO |
692525 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
711937 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
396208, 396210 |
2.5.1.19 | 3-phosphoshikimate 1-carboxyvinyltransferase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
759931 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
688137 |
3.2.1.105 | 3alpha(S)-strictosidine beta-glucosidase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
714624 |
1.1.1.213 | 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
347987, 688137 |
1.1.1.50 | 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
688137 |
1.14.19.79 | 3beta,22alpha-dihydroxysteroid 3-dehydrogenase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
765611 |
2.7.1.148 | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
689692 |
4.2.1.96 | 4a-hydroxytetrahydrobiopterin dehydratase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
5931, 5935, 5937 |
3.6.1.59 | 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase |
nucleus |
DcpS is a nuclear shuttling protein |
GO:0005634 AmiGO QuickGO |
713604 |
3.6.1.59 | 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase |
nucleus |
DcpS is predominantly a nuclear protein, with low levels of in the cytoplasm |
GO:0005634 AmiGO QuickGO |
716896 |
3.6.1.59 | 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase |
nucleus |
nucleocytoplasmic shuttling protein |
GO:0005634 AmiGO QuickGO |
716897 |
3.6.1.62 | 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
716816, 758123, 758538 |
3.6.1.62 | 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase |
nucleus |
hDcp2 is predominantly a nuclear protein, with low levels of in the cytoplasm |
GO:0005634 AmiGO QuickGO |
716896 |
3.1.13.B1 | 5'-3' exoribonuclease |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
751722 |
1.14.18.B1 | 5,6-dihydroxyindole-2-carboxylic acid oxidase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
744413 |
2.1.1.14 | 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase |
nucleus |
nuclear localization is abrogated by the deletion of 107 C-terminal amino acids or the R742A mutation |
GO:0005634 AmiGO QuickGO |
757179 |
2.7.1.105 | 6-phosphofructo-2-kinase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
737997, 751774 |
2.7.1.105 | 6-phosphofructo-2-kinase |
nucleus |
PFKFB3 |
GO:0005634 AmiGO QuickGO |
761915 |
2.7.1.105 | 6-phosphofructo-2-kinase |
nucleus |
PFKFB3 splice variant 5, the carboxyl terminus is required for this localization |
GO:0005634 AmiGO QuickGO |
698929 |
4.2.3.12 | 6-pyruvoyltetrahydropterin synthase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
664165 |
4.2.3.12 | 6-pyruvoyltetrahydropterin synthase |
nucleus |
immunofluorescence, Western blot analysis |
GO:0005634 AmiGO QuickGO |
664165 |
4.2.3.12 | 6-pyruvoyltetrahydropterin synthase |
nucleus |
strong staining in immunohistochemistry |
GO:0005634 AmiGO QuickGO |
664165 |
1.3.1.21 | 7-dehydrocholesterol reductase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
349267 |
7.6.2.4 | ABC-type fatty-acyl-CoA transporter |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
667893 |
6.2.1.1 | acetate-CoA ligase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
744651, 744656, 745887, 746321 |
6.2.1.1 | acetate-CoA ligase |
nucleus |
isoform ACS2 is localized primarily to the nucleus, with a minor amount in the cytosol |
GO:0005634 AmiGO QuickGO |
705678 |
2.3.1.9 | acetyl-CoA C-acetyltransferase |
nucleus |
isozyme AACT2 |
GO:0005634 AmiGO QuickGO |
703818 |
2.3.1.16 | acetyl-CoA C-acyltransferase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
756086 |
2.3.1.16 | acetyl-CoA C-acyltransferase |
nucleus |
ACAA2 resides in the nucleus in significant concentrations and harbors an nuclear localization signal that mediates nuclear import |
GO:0005634 AmiGO QuickGO |
756086 |
3.1.3.2 | acid phosphatase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
664547 |
3.1.3.2 | acid phosphatase |
nucleus |
strong activity detected |
GO:0005634 AmiGO QuickGO |
695210 |
1.13.11.53 | acireductone dioxygenase (Ni2+-requiring) |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
673852, 764433 |
1.13.11.54 | acireductone dioxygenase [iron(II)-requiring] |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
764775 |
4.2.1.3 | aconitate hydratase |
nucleus |
bL21-fused Aco2 protein resides in mitochondria as well as in the cytosol and the nucleus |
GO:0005634 AmiGO QuickGO |
-, 747770 |
3.4.19.1 | acylaminoacyl-peptidase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
732661, 753398 |
3.4.24.81 | ADAM10 endopeptidase |
nucleus |
in untreated cells |
GO:0005634 AmiGO QuickGO |
699697 |
3.4.24.82 | ADAMTS-4 endopeptidase |
nucleus |
the enzyme translocates to the nucleus of apoptotic cells |
GO:0005634 AmiGO QuickGO |
755457 |
3.4.24.B11 | ADAMTS1 endopeptidase |
nucleus |
ADAMTS-1 is present primarily in the nucleus and with a relatively homogeneous distribution in MCF-10A, MCF-7, and MDA-MB-231 cells.Substrate aggrecan is also found in the nuclei of MCF-10A cells, but not entirely colocalized with ADAMTS-1 |
GO:0005634 AmiGO QuickGO |
755133 |
2.4.2.7 | adenine phosphoribosyltransferase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
638170 |
3.1.11.7 | adenosine-5'-diphospho-5'-[DNA] diphosphatase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
750390 |
3.6.1.71 | adenosine-5'-diphospho-5'-[DNA] diphosphatase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
741055, 750390 |
3.6.1.71 | adenosine-5'-diphospho-5'-[DNA] diphosphatase |
nucleus |
the first nuclear localization signal located near the amino terminus of the long-form aprataxin is essential for its nuclear localization |
GO:0005634 AmiGO QuickGO |
739862 |
3.13.2.1 | adenosylhomocysteinase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
731690, 753615, 754428, 754830 |
3.13.2.1 | adenosylhomocysteinase |
nucleus |
immunodetection of enzyme in nuclei of single interstitial cells of renal cortex and outer medula of hte hypoxic rat |
GO:0005634 AmiGO QuickGO |
679105 |
4.6.1.1 | adenylate cyclase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
34784 |
4.6.1.1 | adenylate cyclase |
nucleus |
soluble isozyme |
GO:0005634 AmiGO QuickGO |
693876 |
4.6.1.1 | adenylate cyclase |
nucleus |
soluble isozyme, only in its shortened, active form |
GO:0005634 AmiGO QuickGO |
693876 |
2.5.1.27 | adenylate dimethylallyltransferase |
nucleus |
farnesylated protein |
GO:0005634 AmiGO QuickGO |
706291 |
2.7.4.3 | adenylate kinase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
642558, 663243, 703721, 723448, 723515 |
2.7.4.3 | adenylate kinase |
nucleus |
predominant localization |
GO:0005634 AmiGO QuickGO |
673656 |
2.7.4.3 | adenylate kinase |
nucleus |
predominant nuclear localization |
GO:0005634 AmiGO QuickGO |
691028 |
2.7.7.96 | ADP-D-ribose pyrophosphorylase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
741436, 762060 |
1.1.1.1 | alcohol dehydrogenase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
697214 |
2.3.1.84 | alcohol O-acetyltransferase |
nucleus |
both isoforms CFAT1 and CFAT2 |
GO:0005634 AmiGO QuickGO |
758184 |
2.8.2.2 | alcohol sulfotransferase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
675680 |
2.8.2.2 | alcohol sulfotransferase |
nucleus |
isozyme SULT2B1b, T47D or MCF-7 breast cancer cells, SULT2B1b is not tightly bound in the nuclei |
GO:0005634 AmiGO QuickGO |
675680 |
2.8.2.2 | alcohol sulfotransferase |
nucleus |
the proline- and serine-rich carboxyl extension of SULT2B1b is an important site in the nuclear translocation of this SULT isoform, overview |
GO:0005634 AmiGO QuickGO |
673295 |
1.2.1.3 | aldehyde dehydrogenase (NAD+) |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
711635, 712435 |
1.2.1.3 | aldehyde dehydrogenase (NAD+) |
nucleus |
isoform ALDH3A1 |
GO:0005634 AmiGO QuickGO |
711635 |
1.2.1.5 | aldehyde dehydrogenase [NAD(P)+] |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
689379 |
1.2.1.5 | aldehyde dehydrogenase [NAD(P)+] |
nucleus |
isoform ALDH3A1 |
GO:0005634 AmiGO QuickGO |
711635 |
5.1.3.3 | Aldose 1-epimerase |
nucleus |
of epithelial cells of renal tubules and glomeruli |
GO:0005634 AmiGO QuickGO |
2373 |
5.1.3.3 | Aldose 1-epimerase |
nucleus |
of liver parenchymal cells and small intestine mucosal cells |
GO:0005634 AmiGO QuickGO |
2376 |
1.1.1.21 | aldose reductase |
nucleus |
- |
GO:0005634 AmiGO QuickGO |
738005, 739042 |