EC Number |
Recommended Name |
Localization |
GeneOntology No. |
Reference |
---|
1.11.1.9 | glutathione peroxidase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
396638 |
1.14.11.33 | DNA oxidative demethylase |
nucleolus |
accumulation of YFP-ABH2 construct |
GO:0005730 AmiGO QuickGO |
723671 |
1.14.11.33 | DNA oxidative demethylase |
nucleolus |
nucleolar localization sequence RKRPRR at aa38-aa43 of ABH2, mutation of RKR to AAA within this sequence impaired the nuclear and nucleolar localization of ABH2 in HeLa cells. ABH2 associates with nucleolar proteins NCL, NPM1, and UBF |
GO:0005730 AmiGO QuickGO |
724700 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
nucleolus |
PHF8 colocalizes with B23 and fibrillarin |
GO:0005730 AmiGO QuickGO |
753206 |
1.14.11.66 | [histone H3]-trimethyl-L-lysine9 demethylase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
712775 |
1.14.11.79 | protein-L-histidine (3S)-3-hydroxylase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
764446, 765443 |
1.4.3.1 | D-aspartate oxidase |
nucleolus |
in magnocellular neurons of the rat supraoptic nucleus |
GO:0005730 AmiGO QuickGO |
711719 |
2.1.1.166 | 23S rRNA (uridine2552-2'-O)-methyltransferase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
703879 |
2.1.1.167 | 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
700152, 700492 |
2.1.1.183 | 18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
705680 |
2.1.1.202 | multisite-specific tRNA:(cytosine-C5)-methyltransferase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
736856, 756866, 757702, 758103, 758477 |
2.1.1.203 | tRNA (cytosine34-C5)-methyltransferase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
710135, 758103 |
2.1.1.260 | rRNA small subunit pseudouridine methyltransferase Nep1 |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
-, 719322, 720587, 720589 |
2.1.1.286 | 25S rRNA (adenine2142-N1)-methyltransferase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
723300 |
2.1.1.310 | 25S rRNA (cytosine2870-C5)-methyltransferase |
nucleolus |
the N-terminal domain of the enzyme is important for its nucleolar localization |
GO:0005730 AmiGO QuickGO |
-, 737084 |
2.1.1.313 | 25S rRNA (uracil2634-N3)-methyltransferase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
-, 730508 |
2.1.1.B128 | 28S rRNA (adenine1322-N1)-methyltransferase |
nucleolus |
NML is primarily localized in the nucleolus |
GO:0005730 AmiGO QuickGO |
758419 |
2.1.1.B130 | [histone H3]-N-methyllysine9 N-methyltransferase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
759859 |
2.3.1.B41 | protein-long-chain fatty-acyl-lysine deacylase (NAD+) |
nucleolus |
Sirt6 is enriched in the nucleolus in the G1 phase of the cell cycle, while S phase nucleoli are almost entirely free of Sirt6 |
GO:0005730 AmiGO QuickGO |
730527 |
2.4.1.12 | cellulose synthase (UDP-forming) |
nucleolus |
co-localized with F-actin |
GO:0005730 AmiGO QuickGO |
718750 |
2.7.1.158 | inositol-pentakisphosphate 2-kinase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
738742, 760326 |
2.7.1.158 | inositol-pentakisphosphate 2-kinase |
nucleolus |
preferentially localized in euchromatin and nucleoli, and colocalized with mRNA |
GO:0005730 AmiGO QuickGO |
671904 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
673232 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
nucleolus |
enzyme PI4K230 |
GO:0005730 AmiGO QuickGO |
641806 |
2.7.1.68 | 1-phosphatidylinositol-4-phosphate 5-kinase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
738659 |
2.7.11.21 | polo kinase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
662812, 705986 |
2.7.11.21 | polo kinase |
nucleolus |
Plk3, as long as the nucleolus is intact, and is undetectable during mitosis |
GO:0005730 AmiGO QuickGO |
679094 |
2.7.11.23 | [RNA-polymerase]-subunit kinase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
662973 |
2.7.4.3 | adenylate kinase |
nucleolus |
nucleolar localization is dependent on nutrient availability and active transcription and ribosome assembly and is lost upon oxidative stress |
GO:0005730 AmiGO QuickGO |
723515 |
2.7.7.6 | DNA-directed RNA polymerase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
643551 |
2.8.1.7 | cysteine desulfurase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
738144 |
3.1.13.1 | exoribonuclease II |
nucleolus |
DFC region |
GO:0005730 AmiGO QuickGO |
665808 |
3.1.13.4 | poly(A)-specific ribonuclease |
nucleolus |
nucleolar steady-state localization |
GO:0005730 AmiGO QuickGO |
751744 |
3.1.21.7 | deoxyribonuclease V |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
730709 |
3.1.26.5 | ribonuclease P |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
694828, 694869 |
3.1.26.5 | ribonuclease P |
nucleolus |
nucleolar enzyme form of RNase MRP |
GO:0005730 AmiGO QuickGO |
656352 |
3.1.26.5 | ribonuclease P |
nucleolus |
RNase MRP |
GO:0005730 AmiGO QuickGO |
654201 |
3.1.26.5 | ribonuclease P |
nucleolus |
RNase P, all subunits |
GO:0005730 AmiGO QuickGO |
657340 |
3.1.26.5 | ribonuclease P |
nucleolus |
the enzyme is composed of a catalytic RNA and two proteins, protein PRORP1 is largely confined to the single central nucleolus of the nuclei and only weak in the nucleoplasm |
GO:0005730 AmiGO QuickGO |
729548 |
3.1.3.16 | protein-serine/threonine phosphatase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
698767 |
3.1.3.19 | glycerol-2-phosphatase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
94699 |
3.1.3.2 | acid phosphatase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
680018 |
3.1.3.53 | [myosin-light-chain] phosphatase |
nucleolus |
depending on fixation method for immunohistochemistry, localization of myosin phosphatase target subunit found in nucleus, nucleolus, or cytoplasm |
GO:0005730 AmiGO QuickGO |
665833 |
3.2.2.27 | uracil-DNA glycosylase |
nucleolus |
hSMUG1 accumulates in nucleoli in living cells |
GO:0005730 AmiGO QuickGO |
692963 |
3.2.2.27 | uracil-DNA glycosylase |
nucleolus |
hUNG2 is excluded from nucleoli in living cells, but hUNG2 accumulates in replication foci in the S-phase |
GO:0005730 AmiGO QuickGO |
692963 |
3.4.22.53 | calpain-2 |
nucleolus |
in KRASWT/- cells serum starvation induces CAPN2 expression, nucleolar accumulation |
GO:0005730 AmiGO QuickGO |
754967 |
3.4.22.54 | calpain-3 |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
708013 |
3.4.22.B72 | SENP3 peptidase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
732594 |
3.4.22.B72 | SENP3 peptidase |
nucleolus |
reactive oxygen species cause SENP3 to redistribute from the nucleoli to the nucleoplasm, allowing it to regulate nuclear events |
GO:0005730 AmiGO QuickGO |
714827 |
3.4.22.B72 | SENP3 peptidase |
nucleolus |
SENP3 localizes within the granular component of the nucleolus, a subnucleolar compartment that contains B23/nucleophosmin |
GO:0005730 AmiGO QuickGO |
715705 |
3.4.22.B73 | SENP5 peptidase |
nucleolus |
in interphase, SenP5 resides primarily within the nucleoli, in addition to a cytosolic pool. Relocalization of SenP5 from the nucleoli to the mitochondrial surface at G2/M transition prior to nuclear envelope breakdown |
GO:0005730 AmiGO QuickGO |
715497 |
3.4.22.B73 | SENP5 peptidase |
nucleolus |
localize predominantly to the nucleolus |
GO:0005730 AmiGO QuickGO |
681908 |
3.4.22.B73 | SENP5 peptidase |
nucleolus |
SENP5 expression is chiefly detected in the cytoplasm of tumor cells and in the cytoplasm and/or nucleus of normal epithelium cells |
GO:0005730 AmiGO QuickGO |
716404 |
3.4.22.B73 | SENP5 peptidase |
nucleolus |
SENP5 localizes within the granular component of the nucleolus, a subnucleolar compartment that contains B23/nucleophosmin |
GO:0005730 AmiGO QuickGO |
715705 |
3.4.24.B11 | ADAMTS1 endopeptidase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
755133 |
3.5.4.37 | double-stranded RNA adenine deaminase |
nucleolus |
ADAR2 localizes exclusively to the nucleus and accumulates in the nucleolus. In living cells, editing might be regulated by the intracellular compartmentalization of editing enzymes. ADAR2 shuttles between the nucleolus and the nucleoplasm |
GO:0005730 AmiGO QuickGO |
720090 |
3.5.4.37 | double-stranded RNA adenine deaminase |
nucleolus |
full-length and N-terminally truncated forms of ADAR1 are simultaneously expressed in HeLa cells. Because the N-terminus of ADAR1 contains a nuclear export signal, the full-length protein (150000 Da) localizes predominantly in the cytoplasm, whereas the N-terminally truncated forms (110000 Da) are exclusively nuclear and accumulate in the nucleolus. In living cells, editing might be regulated by the intracellular compartmentalization of editing enzymes. ADAR1 shuttles between the nucleolus, the nucleoplasm and the cytoplasm |
GO:0005730 AmiGO QuickGO |
720090 |
3.6.1.62 | 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
715488 |
3.6.1.62 | 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase |
nucleolus |
predominantly nucleolar |
GO:0005730 AmiGO QuickGO |
670221 |
3.6.1.64 | inosine diphosphate phosphatase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
720583 |
3.6.1.70 | guanosine-5'-diphospho-5'-[DNA] diphosphatase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
740518 |
3.6.1.70 | guanosine-5'-diphospho-5'-[DNA] diphosphatase |
nucleolus |
GFP-aprataxin fusion protein colocalizes with nucleolin, nucleophosmin and UBF-1 in nucleoli. Inhibition of ribosomal DNA transcription alters the distribution of aprataxin in the nucleolus. Down-regulation of nucleolin by RNA interference does not affect aprataxin protein levels but abolishes its nucleolar localization |
GO:0005730 AmiGO QuickGO |
740519 |
3.6.1.71 | adenosine-5'-diphospho-5'-[DNA] diphosphatase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
740518 |
3.6.1.71 | adenosine-5'-diphospho-5'-[DNA] diphosphatase |
nucleolus |
aprataxin localizes at sites of DNA damage induced by high low linear energy transfer radiation |
GO:0005730 AmiGO QuickGO |
741072 |
3.6.1.71 | adenosine-5'-diphospho-5'-[DNA] diphosphatase |
nucleolus |
GFP-aprataxin fusion protein colocalizes with nucleolin, nucleophosmin and UBF-1 in nucleoli. Inhibition of ribosomal DNA transcription alters the distribution of aprataxin in the nucleolus. Down-regulation of nucleolin by RNA interference does not affect aprataxin protein levels but abolishes its nucleolar localization |
GO:0005730 AmiGO QuickGO |
740519 |
3.6.1.B17 | ATP-independent RNA helicase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
-, 734916 |
3.6.4.13 | RNA helicase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
758132, 758198 |
3.6.4.13 | RNA helicase |
nucleolus |
accumulation of DHX9 in nucleoli and its association with rRNA genes only upon ESC |
GO:0005730 AmiGO QuickGO |
756594 |
3.6.5.4 | signal-recognition-particle GTPase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
669585 |
4.1.99.3 | deoxyribodipyrimidine photo-lyase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
-, 652227 |
5.6.1.7 | chaperonin ATPase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
749858 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
747480 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
nucleolus |
DNA Top IIbeta is localized in the nucleolus during interphase, and in the cytoplasm during mitosis |
GO:0005730 AmiGO QuickGO |
716348 |
5.6.2.3 | DNA 5'-3' helicase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
756869 |
6.1.1.10 | methionine-tRNA ligase |
nucleolus |
translocation from the cytoplasm is triggered by insulin, epidermal growth factor, translocation by a proliferation signal, the enzyme is part of the multi-aminoacyl-tRNA synthetase complex in the nucleolus |
GO:0005730 AmiGO QuickGO |
652598 |
6.1.1.2 | tryptophan-tRNA ligase |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
653176 |
6.5.1.4 | RNA 3'-terminal-phosphate cyclase (ATP) |
nucleolus |
- |
GO:0005730 AmiGO QuickGO |
650972 |