EC Number |
Recommended Name |
Localization |
GeneOntology No. |
Reference |
---|
1.1.1.1 | alcohol dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
721749 |
1.1.1.1 | alcohol dehydrogenase |
mitochondrion |
higher enzyme level in mitochondria from cells grown at pH 6.0 than in mitochondria from cells grown at pH 3.7 |
GO:0005739 AmiGO QuickGO |
739328 |
1.1.1.1 | alcohol dehydrogenase |
mitochondrion |
HpADH3 |
GO:0005739 AmiGO QuickGO |
-, 721388 |
1.1.1.1 | alcohol dehydrogenase |
mitochondrion |
KlDH3 and KlADH4 are genes encoding mitochondrial alcohol dehydrogenase activities located within the mitochondria. Ethanol induces the transcription of KlADH4 and, conversely, represses that of KlADH3 |
GO:0005739 AmiGO QuickGO |
668675 |
1.1.1.1 | alcohol dehydrogenase |
mitochondrion |
KmAdh3 possesses an amino-terminal extension as a mitochondrial targeting sequence |
GO:0005739 AmiGO QuickGO |
-, 685652 |
1.1.1.1 | alcohol dehydrogenase |
mitochondrion |
KmAdh4 possesses an amino-terminal extension as a mitochondrial targeting sequence |
GO:0005739 AmiGO QuickGO |
-, 685652 |
1.1.1.100 | 3-oxoacyl-[acyl-carrier-protein] reductase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
704721, 740558 |
1.1.1.103 | L-threonine 3-dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
737579, 738933 |
1.1.1.105 | all-trans-retinol dehydrogenase (NAD+) |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
656260 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
389385, 389391, 389399, 389401, 740914, 762899, 763756 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
mitochondrion |
inner mitochondrial membrane |
GO:0005739 AmiGO QuickGO |
389399 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
mitochondrion |
isoform 3betaHSD2 associates with the inner mitochondrial membrane or outer mitochondrial membrane translocases facing the intermembrane space. Tthis interaction promotes the conformational change needed for full activity. 3betaHSD2 associates with the inner mitochondrial membrane but does not integrate into the membrane. 3betaHSD2 forms a transient association with the translocases Tim50 and Tom22 and with Tim23. This association occurs primarily through the interaction of Tim50 with the N-terminus of 3betaHSD2 and contributes to enzymatic activity. Tim50 knockdown inhibits catalysis of dehydroepiandrostenedione to androstenedione and pregnenolone to progesterone. Although Tim50 knockdown decreases 3betaHSD2 expression, restoration of expression via proteasome and protease inhibition does not rescue activity |
GO:0005739 AmiGO QuickGO |
725447 |
1.1.1.150 | 21-hydroxysteroid dehydrogenase (NAD+) |
mitochondrion |
isoform RDH13 |
GO:0005739 AmiGO QuickGO |
688677 |
1.1.1.178 | 3-hydroxy-2-methylbutyryl-CoA dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
673530, 711851 |
1.1.1.2 | alcohol dehydrogenase (NADP+) |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
286177, 286204, 286214, 654908 |
1.1.1.211 | long-chain-3-hydroxyacyl-CoA dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
-, 288681, 686162, 688119, 723341, 740102, 740106, 740438, 740557, 740641, 741457 |
1.1.1.237 | hydroxyphenylpyruvate reductase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
657023 |
1.1.1.27 | L-lactate dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
689715, 762363 |
1.1.1.27 | L-lactate dehydrogenase |
mitochondrion |
inner compartment, transport and metabolism of L-lactate, overview |
GO:0005739 AmiGO QuickGO |
685322 |
1.1.1.27 | L-lactate dehydrogenase |
mitochondrion |
L-lactate dehydrogenase is restricted to the inner mitochondrial compartments |
GO:0005739 AmiGO QuickGO |
747163 |
1.1.1.27 | L-lactate dehydrogenase |
mitochondrion |
LDH is present in the inner mitochondrial compartments |
GO:0005739 AmiGO QuickGO |
686648 |
1.1.1.27 | L-lactate dehydrogenase |
mitochondrion |
LDH-A |
GO:0005739 AmiGO QuickGO |
-, 685502 |
1.1.1.27 | L-lactate dehydrogenase |
mitochondrion |
mL-LDH is restricted in inner compartment |
GO:0005739 AmiGO QuickGO |
746989 |
1.1.1.277 | 3beta-hydroxy-5beta-steroid dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
-, 389563 |
1.1.1.28 | D-lactate dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
-, 760993 |
1.1.1.28 | D-lactate dehydrogenase |
mitochondrion |
D-lactate dehydrogenase is inserted into the inner membrane of mitochondria through its transmembrane domain located close to the N-terminus of the polypeptide chain in such a way that the protein globule is exposed in the intermembrane space |
GO:0005739 AmiGO QuickGO |
667751 |
1.1.1.284 | S-(hydroxymethyl)glutathione dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
-, 724453, 762615, 762616, 762890, 763054 |
1.1.1.284 | S-(hydroxymethyl)glutathione dehydrogenase |
mitochondrion |
presence of S-nitrosoglutathione, S-nitrosoglutathione reductase and nitrated proteins |
GO:0005739 AmiGO QuickGO |
723896 |
1.1.1.284 | S-(hydroxymethyl)glutathione dehydrogenase |
mitochondrion |
the enzyme contains a mitochondrial targeting peptide |
GO:0005739 AmiGO QuickGO |
763605 |
1.1.1.30 | 3-hydroxybutyrate dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
286514, 286515, 286516, 286517, 286518, 286519, 286521, 286522, 286525, 286527, 286528, 286529, 286530, 286535, 286542, 655126, 655261, 689351 |
1.1.1.30 | 3-hydroxybutyrate dehydrogenase |
mitochondrion |
beta-hydroxybutyrate dehydrogenase from heavy and light mitochondria are isoforms |
GO:0005739 AmiGO QuickGO |
668322 |
1.1.1.30 | 3-hydroxybutyrate dehydrogenase |
mitochondrion |
light and heavy mitochondria, enzyme expression and activity is increased in heavy mitochondria in hibernating state, overview |
GO:0005739 AmiGO QuickGO |
685409 |
1.1.1.30 | 3-hydroxybutyrate dehydrogenase |
mitochondrion |
located on the matrix face of the inner membrane |
GO:0005739 AmiGO QuickGO |
286512, 286513, 286533, 286538 |
1.1.1.300 | NADP-retinol dehydrogenase |
mitochondrion |
isoform RDH13 |
GO:0005739 AmiGO QuickGO |
688677 |
1.1.1.31 | 3-hydroxyisobutyrate dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
688515, 722472 |
1.1.1.34 | hydroxymethylglutaryl-CoA reductase (NADPH) |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
286557, 286560, 286564 |
1.1.1.34 | hydroxymethylglutaryl-CoA reductase (NADPH) |
mitochondrion |
isozyme Hmg1 |
GO:0005739 AmiGO QuickGO |
686736 |
1.1.1.35 | 3-hydroxyacyl-CoA dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
-, 286269, 286588, 286589, 286590, 286591, 286601, 286606, 286607, 286612, 33713, 657049, 657276, 673340, 673530, 684902, 685573, 687573, 690046, 723558 |
1.1.1.35 | 3-hydroxyacyl-CoA dehydrogenase |
mitochondrion |
matrix enzyme |
GO:0005739 AmiGO QuickGO |
286603 |
1.1.1.36 | acetoacetyl-CoA reductase |
mitochondrion |
isozyme AKR1B15.1 |
GO:0005739 AmiGO QuickGO |
740743 |
1.1.1.37 | malate dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
-, 286626, 286627, 286628, 286629, 286630, 286632, 286636, 286637, 286638, 286640, 286641, 286644, 286645, 286646, 286647, 286649, 286652, 286654, 286655, 286656, 286661, 286662, 286663, 286664, 286665, 286669, 286672, 286676, 655486, 656579, 656753, 656883, 656929, 669002, 670193, 679243, 689325, 696067, 700068, 700338, 700824, 721236, 740165, 760668, 760678 |
1.1.1.37 | malate dehydrogenase |
mitochondrion |
highly expressed mMDH1 and lower expressed mMDH2 isoforms |
GO:0005739 AmiGO QuickGO |
713318 |
1.1.1.37 | malate dehydrogenase |
mitochondrion |
inner or outer membrane, m-MDH located in the inner membrane matrix |
GO:0005739 AmiGO QuickGO |
286629 |
1.1.1.37 | malate dehydrogenase |
mitochondrion |
isozyme mMDH |
GO:0005739 AmiGO QuickGO |
711909, 712850 |
1.1.1.37 | malate dehydrogenase |
mitochondrion |
Mdh1, matrix |
GO:0005739 AmiGO QuickGO |
686953 |
1.1.1.37 | malate dehydrogenase |
mitochondrion |
Mdh2 |
GO:0005739 AmiGO QuickGO |
723540 |
1.1.1.37 | malate dehydrogenase |
mitochondrion |
mitochondrial isozyme |
GO:0005739 AmiGO QuickGO |
688101 |
1.1.1.37 | malate dehydrogenase |
mitochondrion |
mitochondrial MDH |
GO:0005739 AmiGO QuickGO |
-, 711519 |
1.1.1.37 | malate dehydrogenase |
mitochondrion |
outer membrane, intermembrane space, inner membrane, matrix |
GO:0005739 AmiGO QuickGO |
-, 286653, 286672 |
1.1.1.38 | malate dehydrogenase (oxaloacetate-decarboxylating) |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
286678, 286681, 286691, 286693, 286698, 656983, 685215, 695884, 741010, 760840 |
1.1.1.39 | malate dehydrogenase (decarboxylating) |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
286704, 286708, 286715, 654651, 654720, 656163, 656983, 657321, 657362, 685215, 685622, 689604, 712417, 723540, 738272, 741121, 761183, 761186, 762109 |
1.1.1.39 | malate dehydrogenase (decarboxylating) |
mitochondrion |
65% of the activity |
GO:0005739 AmiGO QuickGO |
286712 |
1.1.1.39 | malate dehydrogenase (decarboxylating) |
mitochondrion |
isozyme ME2 |
GO:0005739 AmiGO QuickGO |
687568 |
1.1.1.39 | malate dehydrogenase (decarboxylating) |
mitochondrion |
isozyme NAD-ME1 |
GO:0005739 AmiGO QuickGO |
711147 |
1.1.1.39 | malate dehydrogenase (decarboxylating) |
mitochondrion |
isozymes ME2 and ME3 |
GO:0005739 AmiGO QuickGO |
712942 |
1.1.1.39 | malate dehydrogenase (decarboxylating) |
mitochondrion |
isozymes NAD-ME1 and NAD-ME2 |
GO:0005739 AmiGO QuickGO |
711147 |
1.1.1.39 | malate dehydrogenase (decarboxylating) |
mitochondrion |
ME2 |
GO:0005739 AmiGO QuickGO |
713373 |
1.1.1.39 | malate dehydrogenase (decarboxylating) |
mitochondrion |
one of NAD-ME isoforms with MW 110 kDa is located in mitochondria of bundle sheath cells of control and drought-exposed plants, and another isoform of MW 121 kDa is formed in mitochondria of bundle sheath cells under influence of drought. After resuming watering the 121 kDa isoform disappears again. About 90.6% of the total NAD-ME activity is localized in mitochondrial stroma of bundle sheath cells |
GO:0005739 AmiGO QuickGO |
741191 |
1.1.1.39 | malate dehydrogenase (decarboxylating) |
mitochondrion |
predominantly in the matrix space |
GO:0005739 AmiGO QuickGO |
286712 |
1.1.1.40 | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
286715, 286734, 286735, 286738, 728207, 739163, 741010, 761074, 761183, 761332 |
1.1.1.40 | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
mitochondrion |
2 distinct enzyme forms are present in cytosol and in mitochondria |
GO:0005739 AmiGO QuickGO |
286725 |
1.1.1.40 | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
mitochondrion |
both cytosolic and mitochondrial isozymes are more abundant in the insect stage, although they can be immunodetected in the bloodstream forms |
GO:0005739 AmiGO QuickGO |
-, 712042 |
1.1.1.40 | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
mitochondrion |
expression of the mitochondrial ME is upregulated in amastigotes |
GO:0005739 AmiGO QuickGO |
-, 712042 |
1.1.1.40 | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
mitochondrion |
isozyme ME3 |
GO:0005739 AmiGO QuickGO |
687568 |
1.1.1.40 | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
mitochondrion |
mitochondrial isozyme, appears to be clearly more abundant in the insect stage, although it can be immunodetected in the bloodstream form |
GO:0005739 AmiGO QuickGO |
-, 712042 |
1.1.1.40 | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
mitochondrion |
mitochondrial isozyme, the expression of the mitochondrial isozyme seems to be clearly upregulated in amastigotes |
GO:0005739 AmiGO QuickGO |
-, 712042 |
1.1.1.40 | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
mitochondrion |
mitochondrial malic enzyme ME3 |
GO:0005739 AmiGO QuickGO |
712942 |
1.1.1.41 | isocitrate dehydrogenase (NAD+) |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
-, 286749, 286754, 286761, 286762, 286766, 286767, 286774, 654652, 654843, 656118, 657111, 667647, 670544, 670547, 684713, 685719, 712440, 713076, 721381, 740114, 741407, 741458, 760834, 762407 |
1.1.1.41 | isocitrate dehydrogenase (NAD+) |
mitochondrion |
exclusively |
GO:0005739 AmiGO QuickGO |
654914 |
1.1.1.41 | isocitrate dehydrogenase (NAD+) |
mitochondrion |
resticted to |
GO:0005739 AmiGO QuickGO |
740425 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
-, 286782, 286783, 286785, 286792, 286793, 654341, 654649, 654652, 655456, 655663, 656093, 656180, 668697, 669307, 669373, 670236, 670334, 686864, 686899, 689917, 696487, 711119, 739984, 740117, 740583, 760832, 761047, 762409, 762446 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
mitochondrion |
IDH2 |
GO:0005739 AmiGO QuickGO |
712614, 713508 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
mitochondrion |
IDH2 and IDH3 |
GO:0005739 AmiGO QuickGO |
713508 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
mitochondrion |
IDP1 |
GO:0005739 AmiGO QuickGO |
-, 711006 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
mitochondrion |
IDPm |
GO:0005739 AmiGO QuickGO |
712077 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
mitochondrion |
increase in enzyme activity during ischemia, enzyme from ischemic heart mitochondria demonstrates higher activation energy and lower thermal stability and differs in KM-value and regulation |
GO:0005739 AmiGO QuickGO |
670236 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
mitochondrion |
isoenzyme IDP1 |
GO:0005739 AmiGO QuickGO |
684709 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
mitochondrion |
isozyme ICD1, mainly |
GO:0005739 AmiGO QuickGO |
656431 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
mitochondrion |
isozyme IDP1 |
GO:0005739 AmiGO QuickGO |
654367, 656233 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
mitochondrion |
isozyme mICDH |
GO:0005739 AmiGO QuickGO |
656588 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
mitochondrion |
light-inducible isozyme |
GO:0005739 AmiGO QuickGO |
654843 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
mitochondrion |
mitochondrial NADP+-dependent isocitrate dehydrogenase |
GO:0005739 AmiGO QuickGO |
711330 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
mitochondrion |
mitochondrial targeting peptide signal is predicted for IDH1 |
GO:0005739 AmiGO QuickGO |
723129 |
1.1.1.49 | glucose-6-phosphate dehydrogenase (NADP+) |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
287017 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
287077, 677079 |
1.1.1.59 | 3-hydroxypropionate dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
738640 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
760700, 761037 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
mitochondrion |
isozyme 17beta-HSD10 |
GO:0005739 AmiGO QuickGO |
675983 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
mitochondrion |
isozyme AKR1B15.1 |
GO:0005739 AmiGO QuickGO |
740743 |
1.1.1.75 | (R)-aminopropanol dehydrogenase |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
287300, 287301, 287307 |
1.1.1.79 | glyoxylate reductase (NADP+) |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
286409, 287327, 761190 |
1.1.1.79 | glyoxylate reductase (NADP+) |
mitochondrion |
intermembrane space and inner membrane |
GO:0005739 AmiGO QuickGO |
287321 |
1.1.1.79 | glyoxylate reductase (NADP+) |
mitochondrion |
isoform GLYR2 |
GO:0005739 AmiGO QuickGO |
761177 |
1.1.1.8 | glycerol-3-phosphate dehydrogenase (NAD+) |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
667415, 712122 |
1.1.1.8 | glycerol-3-phosphate dehydrogenase (NAD+) |
mitochondrion |
determined by isopycnic gradient centrifugation |
GO:0005739 AmiGO QuickGO |
287358 |
1.1.1.8 | glycerol-3-phosphate dehydrogenase (NAD+) |
mitochondrion |
isoform Gpd2p, contains mitochondrial presequence sufficient for targeting |
GO:0005739 AmiGO QuickGO |
656246 |
1.1.1.8 | glycerol-3-phosphate dehydrogenase (NAD+) |
mitochondrion |
localisation shown in Saccharomyces cerevisiae via GFP-fusion proteins |
GO:0005739 AmiGO QuickGO |
675870 |
1.1.1.8 | glycerol-3-phosphate dehydrogenase (NAD+) |
mitochondrion |
predicted from sequence |
GO:0005739 AmiGO QuickGO |
675870 |
1.1.1.8 | glycerol-3-phosphate dehydrogenase (NAD+) |
mitochondrion |
sn-glycerol 3-phosphate dehydrogenase generates superoxide about equally to each side of the membrane |
GO:0005739 AmiGO QuickGO |
667785 |
1.1.1.80 | isopropanol dehydrogenase (NADP+) |
mitochondrion |
- |
GO:0005739 AmiGO QuickGO |
287362 |