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EC Number
Localization
Commentary
GeneOntology No.
Reference
4.4.1.17
integral to membrane
-
-
94055
,
94058
4.4.1.17
soluble
-
-
94057
4.4.1.17
mitochondrion
-
GO:0005739
AmiGO
QuickGO
651895
,
677440
,
715034
,
729264
,
729740
,
730058
,
730322
,
94056
4.4.1.17
mitochondrion
detected by Western analysis
GO:0005739
AmiGO
QuickGO
653258
4.4.1.17
mitochondrion
during apoptotic stimuli, enzyme translocates to outside the mitochondria, and binds to and suppresses the X-linked inhibitor of apoptosis protein XIAP, leading to activation of caspase-3. The N-terminus of the neuronal glutamate transporter excitatory amino-acid carrier 1 EAAC1 can bind to enzyme which interferes with the enzyme-XIAP association
GO:0005739
AmiGO
QuickGO
679489
4.4.1.17
mitochondrion
integral membrane protein of inner membrane (facing cytoplasmic surface)
GO:0005739
AmiGO
QuickGO
94055
4.4.1.17
mitochondrion
intermembrane space
GO:0005739
AmiGO
QuickGO
94057
,
94058
4.4.1.17
mitochondrion
mitoplast
GO:0005739
AmiGO
QuickGO
94055
4.4.1.17
mitochondrion
novel, non-conservative import pathway: the enzyme precursor is translocated into mitochondria using the MOM19-GIP receptor complex in the outer membrane, independent of ATP-hydrolysis and electrochemical potential as external energy source
GO:0005739
AmiGO
QuickGO
94058
4.4.1.17
mitochondrial inner membrane
-
GO:0005743
AmiGO
QuickGO
94056
,
94057
,
94058
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