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EC Number
GeneOntology No.
separase is abundantly expressed within the cytoplasm of a broad range of human tumor cell lines, including MDA-MB-231 breast carcinoma cells
budding yeast Esp1 is localized to the centrosomes and spindle before anaphase
human separase is associated with centrosomes but not with spindle before anaphase, featuring predominantly cytoplasmic localization in non-dividing cells
in fission yeast Cut1 features similar localization in the beginning of anaphase onset persisting on the spindle until mid-anaphase
prodominant localisation
Separase is present in the cell during the entire cell cycle, but excluded from the nucleus until the metaphase-anaphase transition
in nondividing cells in healthy tissue, immunofluorescence microscopy
tumor cells significantly more abundant, immunofluorescence microscopy
Results 1 - 10 of 17 > >>