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EC Number
Localization
Commentary
GeneOntology No.
Reference
3.4.22.53
membrane
in isolated rat hearts, ischemia induces a time-dependent translocation of m-calpain to the membrane that is not associated with calpain activation
GO:0016020
AmiGO
QuickGO
709566
3.4.22.53
membrane
membrane abnormalities and altered signaling pathways observed in Duchenne muscular dystrophy lymphocytes may be due to the increased association of calpain II onto membrane and cytosol
GO:0016020
AmiGO
QuickGO
686159
3.4.22.53
microsome
3.9% of the activity
-
644045
3.4.22.53
mitochondrion
-
GO:0005739
AmiGO
QuickGO
707559
,
717157
3.4.22.53
mitochondrion
m-calpain is present in the intermembrane space of the mitochondria
GO:0005739
AmiGO
QuickGO
707281
3.4.22.53
nucleolus
in KRASWT/- cells serum starvation induces CAPN2 expression, nucleolar accumulation
GO:0005730
AmiGO
QuickGO
754967
3.4.22.53
nucleus
-
GO:0005634
AmiGO
QuickGO
708140
3.4.22.53
nucleus
0.2% of the activity
GO:0005634
AmiGO
QuickGO
644045
3.4.22.53
nucleus
angiotensin II increases nuclear translocation of intracellular Ca2รพ activated calpain-2 in hypertrophied cardiomyocytes
GO:0005634
AmiGO
QuickGO
754244
3.4.22.53
nucleus
from ES cells and the 8-cell stage to late neurulation stages, CAPN2 is expressed in the cytoplasm and nuclear compartments, with a clear co-localisation with chromatin. Nuclear localization was associated either with active cell mitosis in embryonic stem cells and early developmental stages or with precursor cells later during organogenesis
GO:0005634
AmiGO
QuickGO
687156
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