EC Number   |
KM Value [mM] |
KM Value Maximum [mM] |
Substrate |
Reference  |
|---|
    1.14.99.1 | 0.015 |
- |
arachidonate |
purified isoform PGHS-1, method: direct, O2 |
695888 |
| 1.14.99.1 | 0.0055 |
- |
linoleic acid |
isozyme PGHS-1, in 100 mM Tris-HCl buffer (pH 7.4), at 24°C |
701036 |
| 1.14.99.1 | 0.0068 |
- |
linoleic acid |
isozyme PGHS-2, in 100 mM Tris-HCl buffer (pH 7.4), at 24°C |
701036 |
| 1.14.99.1 | -999 |
- |
more |
the cyclooxygenase reaction shows Michaelis-Menten kinetics over a wide range of oxygen concentrations in the absence of electron donor. Kinetics analysis, overview |
714124 |
| 1.14.99.1 | -999 |
- |
more |
Michaelis-Menten kinetics, overview |
715514 |
| 1.14.99.1 | 0.00295 |
- |
arachidonate |
pH 8.0, 25°C, COX-2 mutant L531P |
715514 |
| 1.14.99.1 | 0.00365 |
- |
arachidonate |
pH 8.0, 25°C, COX-2 mutant L531A |
715514 |
| 1.14.99.1 | 0.00514 |
- |
arachidonate |
pH 8.0, 25°C, COX-2 wild-type COX-2 and mutant N580A |
715514 |
| 1.14.99.1 | 0.00945 |
- |
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoic acid |
pH 8.0, 25°C, COX-2 mutant N580A |
715514 |
| 1.14.99.1 | 0.0368 |
- |
(4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid |
pH 8.0, 25°C, COX-2 mutant N580A |
715514 |
