EC Number   |
Inhibitors |
Structure |
|---|
   7.1.1.1 | 2'-AMP |
- |
   |
| 7.1.1.1 | 2-(4-maleimidoanilino)-naphthalene-6-sulfonic acid |
0.004 mM, 2 h incubation, 75% inhibition of reverse reaction catalyzed by A348C mutant enzyme, 95% inhibition of A390C mutant enzyme after 1 h, 90% inhibition of K424C mutant enzyme after 1 h, 55% inhibition of R425C mutant enzyme after 1h |
|
| 7.1.1.1 | 3-Aminopyridine adenine dinucleotide phosphate |
competitive vs. NADP(H) |
|
| 7.1.1.1 | 5'-AMP |
- |
|
| 7.1.1.1 | acetylpyridine adenine dinucleotide |
- |
|
| 7.1.1.1 | Butane-2,3-dione |
40 mM, almost complete inactivation of enzyme activity in chromatophores after 12 min, NAD+ and NADP+ partially protect, complete protection by a combination of NAD+ and NADP+ |
|
| 7.1.1.1 | Cd2+ |
low concentrations of Cd2+ strongly inhibit revers transhydrogenation |
|
| 7.1.1.1 | Dicyclohexylcarbodiimide |
- |
|
| 7.1.1.1 | N,N'-dicyclohexylcarbodiimide |
NADH protects the enzyme against inhibition by N,N'-dicyclohexylcarbodiimide, while NADP+ , and to a lesser extent NADPH increase the rate of inhibition |
|
| 7.1.1.1 | N,N'-dicyclohexylcarbodiimide |
about 12% residual activity after 180 min at 0.5 mM |
|
