EC Number   |
Inhibitors |
Structure |
|---|
    6.1.1.6 | (3R,5S)-1-[(6-amino-9H-purin-9-yl)acetyl]-5-carbamoylpyrrolidin-3-yl L-lysylsulfamate |
strong inhibitory effect |
   |
| 6.1.1.6 | (4R)-1-[(3-chloro-4-hydroxyphenyl)acetyl]-4-[(L-lysylsulfamoyl)oxy]-L-prolinamide |
strong inhibitory effect |
|
| 6.1.1.6 | (4S)-1-(3-bromo-4-hydroxybenzyl)-4-[hydroxy(L-lysyl)amino]-L-prolinamide |
strong inhibitory effect |
|
| 6.1.1.6 | 2'-deoxyadenosine 5'-triphosphate |
- |
|
| 6.1.1.6 | 2'-O-methyladenosine 5'-triphosphate |
- |
|
| 6.1.1.6 | 2-(2-([4-(methyl)-benzoyl]imino)benzothiazol-3-yl)butanoic acid |
i.e. BC-K01 |
|
| 6.1.1.6 | 2-(5,6-difluoro-2-([3-(trifluoromethyl)benzoyl]imino)benzo[d]thiazol-3(2H)-yl)butanoic acid |
i.e. BC-K-YH16899, shows three to sixfold better inhibition of KRS as BC-K01 in most of the assays and better volume of distribution in vivo |
|
| 6.1.1.6 | 3'-Deoxyadenosine 5'-triphosphate |
- |
|
| 6.1.1.6 | 3'-Deoxyadenosine 5'-triphosphate |
inhibitor in aminoacylation, good substrate in ATP-diphosphate exchange |
|
| 6.1.1.6 | 3'-O-Methyladenosine 5'-triphosphate |
- |
|
