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EC Number
Inhibitors
Commentary
Structure
5.4.3.2
4,5-dehydro-(S)-lysine
suicide inactivator
5.4.3.2
4-thia-L-lysine
substrate analogue, generates a stable analogues of the alpha-Lys radical
5.4.3.2
Co2+
0.1 mM, 80% inhibition
5.4.3.2
Fe2+
in a [4Fe-4S] cluster
5.4.3.2
iodoacetic acid
-
5.4.3.2
NEM
-
5.4.3.2
PCMB
-
5.4.3.2
S-adenosylhomocysteine
competitive towards S-adenosylmethionine
5.4.3.2
S-aminoethylcysteine
-
5.4.3.2
SDS
50 mM, the rate of inactivation decreases in the presence of L-Lys, S-adenosylmethionine or S-adenosylhomocysteine. The SDS-dissociated enzyme can be slightly reactivated by removal of the detergent by gel filtration or dialysis
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