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EC Number
Inhibitors
Commentary
Structure
5.1.3.17
CHAPS
-
5.1.3.17
heparin hexasaccharide
mechanism of product inhibition of the enzyme: 2-O- and 6-O-sulfation of heparan sulfate keeps the C5 carbon of L-iduronic acid away from the active-site tyrosine residues, binding structure, detailed overview
5.1.3.17
KCl
stimulates, maximal effect at 0.1 M, inhibition at higher concentrations
5.1.3.17
more
CHAPS and n-octyl beta-D-glucoside slightly inhibite the activity, the effect of Triton X-100 is negligible
5.1.3.17
n-octyl-beta-D-glucoside
-
5.1.3.17
NaCl
stimulates, maximal effect at 0.05 M, inhibition at higher concentrations
5.1.3.17
sodium deoxycholate
complete inhibition at 0.1%
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