EC Number |
Inhibitors |
Structure |
---|
4.1.2.5 | 2-mercaptoethanol |
activity is decreased to 20% of the original by treatment with cysteine plus mercaptoethanol. Most of the loss is regained on incubation with pyridoxal 5'-phosphate |
|
4.1.2.5 | acetaldehyde |
the enzymic cleavage of L-threonine stops when about 30% of the amino acid is converted to glycine and acetaldehyde. By dialysis of the incubation medium against buffer the full activity of the enzyme is restored, product inhibition |
|
4.1.2.5 | Cu2+ |
- |
|
4.1.2.5 | cysteine |
activity is decreased to 20% of the original by treatment with cysteine plus mercaptoethanol. Most of the loss is regained on incubation with pyridoxal 5'-phosphate |
|
4.1.2.5 | glycine |
the enzymic cleavage of L-threonine stops when about 30% of the amino acid is converted to glycine and acetaldehyde. By dialysis of the incubation medium against buffer the full activity of the enzyme is restored, product inhibition |
|
4.1.2.5 | Hg2+ |
- |
|
4.1.2.5 | hydroxylamine |
1 mM, complete inhibition |
|
4.1.2.5 | p-chloromercuribenzoate |
0.01 mM, complete inhibition |
|
4.1.2.5 | Semicarbazide |
1 mM, complete inhibition |
|