EC Number   |
Inhibitors |
Structure |
|---|
   3.9.1.3 | bovine serum albumin |
minimal effects on activity with the exception of a 35% activity decrease in Tris/HCl |
 |
| 3.9.1.3 | Ca2+ |
73% residual activity at 5 mM |
  |
| 3.9.1.3 | CaCl2 |
1 mM, 40% decrease of activity in HEPES and a 15% decrease in Tris/HCl buffer |
|
| 3.9.1.3 | CuCl2 |
1 mM, almost completely inhibits enzyme activity |
|
| 3.9.1.3 | EDTA |
2 mM, negative effect on activity |
|
| 3.9.1.3 | Inhibitor-2 |
isoform PP1, but not PP2A, is inhibited by inhibitor-2 |
|
| 3.9.1.3 | MgCl2 |
1 mM, 10-20% decrease in all buffers except HEPES |
|
| 3.9.1.3 | more |
not inactivated by EDTA |
|
| 3.9.1.3 | more |
insensitive towards okadaic acid and EDTA |
|
| 3.9.1.3 | more |
isoform PP1 is unaffected by 3 nM okadaic acid |
|
