EC Number   |
Inhibitors |
Structure |
|---|
   3.7.1.25 | Ag+ |
Ag+ concentrations in the range 0.001-0.01 mM lower the activity to less than 50% of its uninhibited value |
   |
| 3.7.1.25 | Cu2+ |
Cu2+ concentrations in the range 0.001-0.01 mM lower the activity to less than 50% of its uninhibited value |
|
| 3.7.1.25 | Cu2+ |
- |
|
| 3.7.1.25 | iodoacetamide |
2 mM iodoacetate inhibits the enzyme activity to 50% or less of its uninhibited value after 15 min incubation with the enzyme at 0°C |
|
| 3.7.1.25 | Mn2+ |
the activity of isoform HODHI is decreased by about 50% in the presence of Mn2+ |
|
| 3.7.1.25 | more |
EDTA shows no significant inhibitory effect |
|
| 3.7.1.25 | p-chloromercuribenzoate |
0.2 mM p-chloromercuribenzoate inhibits the enzyme activity to 50% or less of its uninhibited value immediately after incubation with the enzyme at 0°C |
|
| 3.7.1.25 | p-chloromercuribenzoate |
isoform HODHI is inactivated to a much greater extent (90%) by p-chloromercuribenzoate than is isoform HODHII (35%) |
|
| 3.7.1.25 | sodium arsenite |
0.2 mM sodium arsenite inhibits the enzyme activity to 50% or less of its uninhibited value after 15 min incubation with the enzyme at 0°C |
|
| 3.7.1.25 | Zn2+ |
- |
|
