EC Number |
Inhibitors |
Structure |
---|
3.6.1.6 | 1,10-phenanthroline |
2 mM, 66% inhibition |
|
3.6.1.6 | 2,2'-bipyridyl |
2 mM, 64% inhibition |
|
3.6.1.6 | ADP |
1 mM, 27% inhibition of thiamin-diphosphatase activity, competitive |
|
3.6.1.6 | AMP |
slight competitive inhibition of thiamin-diphosphatase activity |
|
3.6.1.6 | AMP |
0.07 mM, , 50% inhibition, type B enzyme |
|
3.6.1.6 | ATP |
slight competitive inhibition of thiamin-diphosphatase activity |
|
3.6.1.6 | ATP |
- |
|
3.6.1.6 | ATP |
inhibits enzyme form A and B2 from mitochondria |
|
3.6.1.6 | ATP |
IC50 for isoenzyme 1 is 6.5 mM, IC50 for isoenzyme 2 is 4.0 mM |
|
3.6.1.6 | Ca2+ |
about 90% inhibition at 10 mM |
|