EC Number |
Inhibitors |
Structure |
---|
3.4.24.36 | 1,10-phenanthroline |
inactivation by dialysis against 1,10-phenanthroline, reactivation of apoenzyme by Zn2+, partially by Cu2+, Co2+, Cd2+ or Ni2+, not by Hg2+, Ca2+, Fe2+, Pb2+, Ba2+, Sn2+, Mg2+, Mn2+, Fe3+ or Ag+; strong, 1 mM, Zn2+ reverses, bovine serum albumin as substrate |
|
3.4.24.36 | 1,10-phenanthroline |
- |
|
3.4.24.36 | 2,2'-bipyridyl |
strong, Zn2+ reverses, bovine serum albumin as substrate |
|
3.4.24.36 | 2-mercaptoethylamine |
Zn2+ reverses, bovine serum albumin as substrate |
|
3.4.24.36 | 8-hydroxyquinoline |
Zn2+ reverses, bovine serum albumin as substrate |
|
3.4.24.36 | Benzyloxycarbonyl-Tyr-Leu-NHOH |
i.e. hydroxamate-derivatized dipeptide, strong, azocasein as substrate |
|
3.4.24.36 | EDTA |
strong, Zn2+ reverses, bovine serum albumin as substrate |
|
3.4.24.36 | EGTA |
strong, Zn2+ reverses, bovine serum albumin as substrate |
|
3.4.24.36 | more |
no inhibition by carboxymethyl derivative of Phe-Leu or hydroxamate derivatives of Leu or Tyr |
|
3.4.24.36 | more |
degradation of MARCKS-related protein MRP is inhibited by protein kinase C-dependent phosphorylation of MRP |
|