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EC Number
Inhibitors
Commentary
Structure
3.4.21.110
anti-ScpA antibody
blocks internalization of streptococci and neutralizes the C5a peptidase acitvity, enabling recruitment of polymorphoneutrophil leukocytes to sites of infection
3.4.21.110
anti-ScpA antibody
rise in convalescent anti-SCPA antibody in all children aged 2-12 years, mean convalescent anti-SCPA antibody level is twice the level of mean actue anti-SCPA antibody, which is statistically significant
3.4.21.110
anti-ScpA antibody
reduces group A streptococci colonization of nasal mucosa-associated lymphoid tissue administered alone or with cholera toxin
3.4.21.110
anti-ScpA antibody
-
3.4.21.110
anti-SCPB antibody
also provides protection against group A streptococcal infection
3.4.21.110
Ca2+
inhibition at 10 mM
3.4.21.110
EDTA
inhibition at 5 mM
3.4.21.110
Mn2+
inhibition at 10 mM
3.4.21.110
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no inhibitor: EDTA
3.4.21.110
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a high degree of group A streptococci colonization of nasal mucosa-associated lymphoid tissue in control mice immunized with phosphate-buffered saline only
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