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EC Number
Inhibitors
Commentary
Structure
3.4.16.2
(3R,4R)-4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-1-(2,2-dimethylpropyl)-3-(4-fluorophenyl)piperidine
compound shows improved oral bioavailabilities
3.4.16.2
2-[4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-5-yl]-1-(2-phenylethyl)piperidin-4-yl]pyridine
most potent compound in the series
3.4.16.2
angiotensin I
inhibits the mutant DELTA317-496 in a dose-dependent manner
3.4.16.2
angiotensin II
IC50: 3 mM, inhibits hydrolysis of Gly-Pro-4-nitroanilide
3.4.16.2
angiotensin II
IC50: 0.1 mM
3.4.16.2
angiotensin II
IC50: 0.002 mM
3.4.16.2
angiotensin II
-
3.4.16.2
angiotensin III
inhibits the mutant DELTA317-496 in a dose-dependent manner
3.4.16.2
anti-PRCP
-
3.4.16.2
antipain
IC50: 0.05 mM
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