EC Number   |
Inhibitors |
Structure |
|---|
   3.4.11.3 | (2-[[(1-[[3-(4-hydroxybenzyl)-5-(L-norleucylamino)phenyl]carbonyl]-L-prolyl)amino]methyl]phenyl)acetic acid |
- |
   |
| 3.4.11.3 | (2-[[(1-[[3-(4-hydroxybenzyl)-5-(L-valylamino)phenyl]carbonyl]-L-prolyl)amino]methyl]phenyl)acetic acid |
- |
|
| 3.4.11.3 | (2-[[(N-[[3-(4-hydroxybenzyl)-5-(L-norleucylamino)phenyl]carbonyl]-L-isoleucyl)amino]methyl]phenyl)acetic acid |
- |
|
| 3.4.11.3 | (2-[[(N-[[3-(4-hydroxybenzyl)-5-(L-norleucylamino)phenyl]carbonyl]-L-leucyl)amino]methyl]phenyl)acetic acid |
- |
|
| 3.4.11.3 | (2-[[(N-[[3-(4-hydroxybenzyl)-5-(L-valylamino)phenyl]carbonyl]-L-isoleucyl)amino]methyl]phenyl)acetic acid |
- |
|
| 3.4.11.3 | (2-[[(N-[[3-amino-5-(4-hydroxybenzyl)phenyl]carbonyl]-L-isoleucyl)amino]methyl]phenyl)acetic acid |
- |
|
| 3.4.11.3 | 1,10-phenanthroline |
- |
|
| 3.4.11.3 | 1,10-phenanthroline |
0.1 mM, 83% inhibition. 0.01 mM, 10% inhibition |
|
| 3.4.11.3 | 1,10-phenanthroline |
competition between 1,10-phenanthroline and the substrate only in presence of EDTA. Inhibitory effect of EDTA plus 1,10-phenanthroline can be completely reversed by Zn2+. Ca2+ and Mg2+ increase the potency of Zn2+ for this process |
|
| 3.4.11.3 | 1,10-phenanthroline |
IC50: 0.2 mM. Inhibitory effect is substantially potentiated by both EDTA and EGTA. A combined and complete inhibition of the enzyme activity by 0.1 mM EDTA and 0.1 mM 1,10-phenanthroline can be prevented in the presence of 0.04-0.1 mM ZnCl2 |
|
