EC Number |
Inhibitors |
Structure |
---|
3.1.5.B1 | acycloguanosine |
- |
|
3.1.5.B1 | amrinone |
IC50 value below 250 microM, Hill coefficient between 0.5 and 1.5 |
|
3.1.5.B1 | cephalosporin C |
zinc salt, inhibition is largely attributable to zinc |
|
3.1.5.B1 | dimedone |
oxidization in the presence of dimedone results in multiple cysteine residues displaying formation of sulfenic acid. Cys341-Cys350 is the predominant intrachain disulfide bond formed |
|
3.1.5.B1 | ergotamine |
IC50 value below 250 microM, Hill coefficient between 0.5 and 1.5 |
|
3.1.5.B1 | H2O2 |
90% inhibition at 0.1 mM. dNTPase activity of SAMHD1 is reversibly inhibited by oxidation, addition of dithiothreitol restores the activity. Oxidation prevents subunit oligomerization |
|
3.1.5.B1 | Hexestrol |
IC50 value below 250 microM, Hill coefficient between 0.5 and 1.5 |
|
3.1.5.B1 | L-thyroxine |
IC50 value below 250 microM, Hill coefficient between 0.5 and 1.5 |
|
3.1.5.B1 | lomofungin |
IC50 value below 250 microM, Hill coefficient between 0.5 and 1.5 |
|
3.1.5.B1 | montelukast |
IC50 value below 250 microM, Hill coefficient between 0.5 and 1.5 |
|