EC Number |
Inhibitors |
Structure |
---|
2.8.1.2 | 1-(2,4-dihydroxyphenyl)-2-[(4-hydroxy-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl)sulfanyl]ethan-1-one |
more than 80% inhibition at 0.01 mM |
|
2.8.1.2 | 2-mercaptoethanol |
high concentrations |
|
2.8.1.2 | 2-mercaptopropionic acid |
uncompetitive inhibitor with respect to 3-mercaptopyruvate |
|
2.8.1.2 | 2-oxobutyrate |
uncompetitive inhibition |
|
2.8.1.2 | 2-[2-[(4-oxo-3,4,4a,8a-tetrahydroquinazolin-2-yl)sulfanyl]acetamido]thiophene-3-carboxamide |
more than 80% inhibition at 0.01 mM |
|
2.8.1.2 | 2-[[2-(1,4-dihydronaphthalen-1-yl)-2-oxoethyl]sulfanyl]-6-methylpyrimidin-4(3H)-one |
more than 80% inhibition at 0.01 mM, almost inactive towards cystathionine gamma-lyase and cystathionine beta-synthase, very low inhibiution of thiosulfate sulfurtransferase, Type II |
|
2.8.1.2 | 3-Chloropyruvate |
one-on-one manner of inactivation, pseudo first-order kinetics |
|
2.8.1.2 | 3-Mercaptopropionic acid |
non-competitive inhibitor |
|
2.8.1.2 | 3-[(benzenesulfonyl)amino]benzoic acid |
more than 80% inhibition at 0.01 mM |
|
2.8.1.2 | alpha-Ketobutyrate |
uncompetitive inhibitor with respect to 3-mercaptopyruvate, 50% inhibition at 13.7 mM |
|