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EC Number
Inhibitors
Commentary
Structure
2.7.7.50
2'-fluoro-2'-deoxy-GTP
-
2.7.7.50
2-amino-6-chloropurine-ribose triphosphate
-
2.7.7.50
3'-deoxy-GTP
-
2.7.7.50
3'-O-Methyl-GTP
-
2.7.7.50
3-[(5Z)-5-(2,3-dichlorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoic acid
-
2.7.7.50
3-[(5Z)-5-(2,4-dichlorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoic acid
-
2.7.7.50
3-[(5Z)-5-(4-tert-butylbenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoic acid
compound shows significant antiviral activity in a dengue virus subgenomic replicon assay and is able to reduce the replication of infectious West Nile virus and yellow fever virus in cell culture with low toxicity
2.7.7.50
6-methylthio-GTP
-
2.7.7.50
6-thio-GTP
-
2.7.7.50
7-methyl-GTP
-
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