EC Number |
Inhibitors |
Structure |
---|
2.6.1.21 | 2-Amino-3-butenoate |
D-alanine in a 10fold excess over vinylglycin affords a 70% protection against inactivation; i.e. vinylglycine, little if any inactivation in absence of 2-oxoglutarate as cosubstrate, in presence of 2-oxoglutarate pseudo-first order kinetics inactivation, inactivation mechanism |
|
2.6.1.21 | 2-Amino-3-butenoate |
i.e. vinylglycine, little if any inactivation in absence of 2-oxoglutarate as cosubstrate, in presence of 2-oxoglutarate pseudo-first order kinetics inactivation, inactivation mechanism |
|
2.6.1.21 | 3-Methyl-2-benzothiazolone hydrazone hydrochloride |
- |
|
2.6.1.21 | aminooxyacetic acid |
0.0001 mM, 50% inhibition |
|
2.6.1.21 | Aminoxyacetate |
0.01 mM, 90% inhibition |
|
2.6.1.21 | beta-Chloro-D-alanine |
catalyzes alpha,beta elimination to yield pyruvate, chloride and ammonia, loss of activity during beta-elimination in presence of D-alanine and 2-oxoglutarate, a potent competitive inhibitor vs. D-alanine |
|
2.6.1.21 | beta-Chloro-D-alanine |
0.025, 56% inhibition |
|
2.6.1.21 | CaCl2 |
45 mM, 50% inhibition |
|
2.6.1.21 | cysteine |
inhibition of D- and L-transamination of D-alanine to 2-oxoglutarate |
|
2.6.1.21 | D-2-aminobutanoate |
inhibition of D- and L-transamination of D-alanine to 2-oxoglutarate, weak |
|