EC Number   |
Inhibitors |
Structure |
|---|
    2.1.1.148 | (2R)-2-[(3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazin-6-yl)sulfanyl]propanoic acid |
6% inhibition at 0.1 mM |
   |
| 2.1.1.148 | (heptanoyl[[(4R)-2-phenyl-3-(phenylcarbonyl)-1,3-thiazolidin-4-yl]methyl] amino)acetic acid |
- |
|
| 2.1.1.148 | 10-methyl-5,8-dideazafolate |
0.2 mM, 90% inhibition |
|
| 2.1.1.148 | 10-propargylfolate |
0.2 mM, 85% inhibition |
|
| 2.1.1.148 | 2-(furan-2-yl)-3-hydroxynaphthalene-1,4-dione |
inhibits the NADPH oxidation and 2'-deoxythymidine-5'-monophosphate-forming activities of ThyX in vitro |
|
| 2.1.1.148 | 2-hydroxy-3-(4-methoxyphenyl)naphthalene-1,4-dione |
inhibits the NADPH oxidation and 2'-deoxythymidine-5'-monophosphate-forming activities of ThyX in vitro |
|
| 2.1.1.148 | 2-hydroxy-3-propylnaphthalene-1,4-dione |
inhibits the NADPH oxidation and 2'-deoxythymidine-5'-monophosphate-forming activities of ThyX in vitro, significant decrease of 1.22 log (17fold) in the colonization loads with Helicobacter pylori of mice treated with the molecule |
|
| 2.1.1.148 | 2-[4-fluoro-3-(trifluoromethyl)phenyl]-3-hydroxynaphthalene-1,4-dione |
inhibits the NADPH oxidation and 2'-deoxythymidine-5'-monophosphate-forming activities of ThyX in vitro |
|
| 2.1.1.148 | 4-(3-(3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl)propanoyl)-N-phenylpiperazine-1-carboxamide |
- |
|
| 2.1.1.148 | 4-[3-(3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)propanoyl]-N-phenylpiperazine-1-carboxamide |
- |
|
