EC Number   |
Inhibitors |
Structure |
|---|
   1.8.5.1 | beauvericin |
BEA, an ionophore, that induces oxidative stress, acts as an antimicrobial and as an enzyme inhibitor. Its cytotoxicity is mostly due to the selective ionophore (channel-forming) activity on biological membranes, which allows a flux of cations, particularly Ca2+, into the cell |
   |
| 1.8.5.1 | Ca2+ |
5 mM, 34% loss of activity |
|
| 1.8.5.1 | Cd2+ |
5 mM CdCl2, complete loss of activity |
|
| 1.8.5.1 | Co2+ |
- |
|
| 1.8.5.1 | Cu2+ |
0.1 mM CuSO4, 98% inhibition |
|
| 1.8.5.1 | Cu2+ |
0.1 mM CuSO4, 43% loss of activity |
|
| 1.8.5.1 | Cyanate |
500 mM, 15% inhibition |
|
| 1.8.5.1 | dehydroascorbate |
at high concentrations |
|
| 1.8.5.1 | diazinon |
about 40% inhibition |
|
| 1.8.5.1 | Fe2+ |
0.1 mM FeSO4, 34% loss of activity |
|
