EC Number   |
Inhibitors |
Structure |
|---|
    1.14.99.39 | 1,2-dimethylcyclopropane |
22 mM, 93% inhibition, mechanism-based inactivator, ammonia enhances the rate of inactivation |
   |
| 1.14.99.39 | 1,3-phenylenediamine |
0.05 mM, 93% inhibition, mechanism-based inactivator, ammonia enhances the rate of inactivation |
|
| 1.14.99.39 | 1,7-octadiyne |
17OD, complete inhibition, inactivation of NH4+-dependent O2 uptake by Nitrosomonas europaea in a time- and concentration-dependent manner. The effects of 17OD are specific for ammonia-oxidizing activity (17OD has no inhibitory effect on NH2OH-dependent O2 uptake), and de novo protein synthesis is required to reestablish this activity in cells exposed to 17OD. NH4Cl does not protect against inactivation of ammonia-oxidizing activity by 17OD under the conditions tested. 17OD is an irreversible inactivator of AMO |
|
| 1.14.99.39 | 1-hexyne |
mechanism-based inactivator, ammonia enhances the rate of inactivation |
|
| 1.14.99.39 | 3-Aminophenol |
0.25 mM, 39% inhibition |
|
| 1.14.99.39 | 3-hexyne |
mechanism-based inactivator, ammonia enhances the rate of inactivation |
|
| 1.14.99.39 | 4-chloroaniline |
0.25 mM, 20% inhibition |
|
| 1.14.99.39 | Acetylene |
- |
|
| 1.14.99.39 | Acetylene |
mechanism-based inactivator, ammonia slows the rate of inactivation |
|
| 1.14.99.39 | Acetylene |
mechanism-based inhibitor, specifically interacts with catalytically active ammonia monooxygenase |
|
