EC Number   |
Inhibitors |
Structure |
|---|
    1.14.16.2 | (6R)-L-erythro-1',2'-dihydroxypropyltetrahydropterin |
80% inhibition when the enzyme is preincubated with (6R)-L-erythro-1',2'-dihydroxypropyltetrahydropterin. Inhibition was attenuated by simultanious addition of dopamine |
   |
| 1.14.16.2 | (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin |
i.e. BH4, cofactor, complex regulation by the cofactor including both enzyme inactivation and conformational stabilization, competitive inhibition, synergistically with DTT |
|
| 1.14.16.2 | (6S)-L-erythro-1',2'-dihydroxypropyltetrahydropterin |
80% inhibition when the enzyme is preincubated with (6S)-L-erythro-1',2'-dihydroxypropyltetrahydropterin |
|
| 1.14.16.2 | 1,10-phenanthroline |
- |
|
| 1.14.16.2 | 1,10-phenanthroline |
complete |
|
| 1.14.16.2 | 1,2,3,4-tetrahydropapaveroline |
50% inhibition at 7.5 microM |
|
| 1.14.16.2 | 2,2'-dipyridyl |
- |
|
| 1.14.16.2 | 2,4-diamino-6-dihydroxypropyl-5,6,7,8-tetrahydropterin |
competitive against (6R)-L-erythro-tetrahydrobiopterin |
|
| 1.14.16.2 | 2-hydroxyestradiol-17beta |
noncompetitive |
|
| 1.14.16.2 | 2-methyl-L-tyrosine |
- |
|
