EC Number   |
Inhibitors |
Structure |
|---|
    1.13.11.49 | 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) |
substrate inhibition at higher concentrations over 0.2 mM |
   |
| 1.13.11.49 | ammonium |
- |
|
| 1.13.11.49 | azide |
- |
|
| 1.13.11.49 | azide |
at 70 microM 44% inhibition, at 700 microM 89% inhibition |
|
| 1.13.11.49 | chloride |
mixed inhibitor |
|
| 1.13.11.49 | chloride |
upon cooperative binding of Cl-, Cld remains pentacoordinate and high-spin |
|
| 1.13.11.49 | chloride |
cooperative binding of Cl- to Cld drives formation of a hexacoordinate, high-spin aqua heme |
|
| 1.13.11.49 | chloride |
weak mixed inhibitor that modifies the EPR signal of as-prepared samples |
|
| 1.13.11.49 | Chlorite |
decrease of activity above 20 mM, complete inhibition at 225 mM |
|
| 1.13.11.49 | Chlorite |
irreversibly inactivates the enzyme after 17000 turnovers (per heme) and with a half-life of 0.39 min, resulting in bleaching of the heme chromophore. Guaiacol offers incomplete protection of the enzyme from inactivation |
|
