EC Number   |
Inhibitors |
Structure |
|---|
    1.12.1.2 | CdSO4 |
1 mM, complete inhibition |
   |
| 1.12.1.2 | CuCl2 |
0.2 mM, complete inhibition |
|
| 1.12.1.2 | cyanide |
1 mM, 33% inhibition |
|
| 1.12.1.2 | diethyl dicarbonate |
chemical modification of active site His residues results in reduced enzymatic hydrogenase and diaphorase activities, pH-dependence and kinetics of modifications/inactivation |
|
| 1.12.1.2 | DTNB |
modification of thiol groups of activated enzyme results in rapid inactivation of both activities, modification of the residues of nonactivated enzyme has small effects on the enzyme activities, pH-dependence and kinetics of modifications/inactivation |
|
| 1.12.1.2 | glutathione |
above 0.1 mM: inactivation, up to 0.1 mM: activation |
|
| 1.12.1.2 | HgCl2 |
0.001 mM, complete inhibition |
|
| 1.12.1.2 | high ionic strength |
200 mM phosphate buffer, 70% inhibition |
|
| 1.12.1.2 | iodoacetate |
100 mM, 36% inhibition |
|
| 1.12.1.2 | iodoacetate |
1 mM, 10% inhibition |
|
