EC Number   |
Inhibitors |
Structure |
|---|
   1.11.1.12 | (1S,3R)-RSL3 |
a selective GPx4 inhibitor, causes a decrease in intracellular ATP levels after 24 h in primary pancreatic rat islets |
 |
| 1.11.1.12 | (1S,3R)-RSL3 |
disrupts mitochondrial morphology and provokes strong mitochondrial impairment |
|
| 1.11.1.12 | 2-chloro-N-(3-chloro-4-methoxyphenyl)-N-[(1S)-2-(phenylethylethylamino)-2-oxo-1-(thiophen-2-yl)ethyl]acetamide |
i.e. ML162 |
|
| 1.11.1.12 | alpha-tocopherol |
complete inhibition of glutathione oxidation |
  |
| 1.11.1.12 | deoxycholate |
- |
|
| 1.11.1.12 | deoxycholate |
in reaction with cumene hydroperoxide and linoleic acid hydroperoxide |
|
| 1.11.1.12 | ferrostatin-1 |
along with the prevention of beta-cell death, siGPx4-mediated induction of lipid peroxidation and ATP depletion are reduced significantly in the presence of ferroptosis inhibitor ferrostatin-1 at 0.001 mM |
|
| 1.11.1.12 | iodoacetate |
- |
|
| 1.11.1.12 | iodoacetate |
2 mM, complete inhibition |
|
| 1.11.1.12 | Mercaptosuccinate |
0.1 mM |
|
